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L Tabár

Publications and source records attributed to L Tabár.

At least 37 records · Page 2Linked to original sources

The Swedish randomised mammography screening trials: analysis of their effect on the breast cancer related excess mortality.

OBJECTIVE: To apply an indirect method for estimation of the breast cancer related excess mortality in the Swedish randomised mammography screening trials. SETTING: Randomised trials on mammography screening have, in Sweden, been performed in the counties of Kopparberg (W) and Ostergötland (E), the so called WE study, and in the three largest cities in Sweden, Stockholm (southern part), Gothenburg, and Malmö. An overview of the trials was presented in the Lancet in 1993 and included 156,911 women in the invited group and 125,866 in the control group. METHODS: The excess mortality in the breast cancer subgroups was estimated by indirect standardisation using official national cause of death statistics according to Statistics Sweden as a reference. RESULTS: The estimated reduction of the breast cancer related mortality was 24% for the whole group (40-74 years at randomisation). The corresponding figures for the age groups 40-49, 50-59, and 60-69 years were 6%, 28%, and 34% respectively. CONCLUSION: The results are very similar to those presented earlier based on the traditional comparison of the breast cancer mortality in the invited and in the control group. This analysis further strengthens previous reports on a beneficial effect of mammography screening, which is especially pronounced in the age group 50-69.

Adult↗

One- versus two-view mammography screening. A prospective population-based study.

In order to compare mammography screening with one versus two views, a prospective population-based study was carried out. Mammograms from 12,636 women aged 40 to 54 years were examined first as one-view screening and later as two-view screening. The initial results showed that two-view screening resulted in 349 recalls, 72 surgical biopsies, and 32 breast cancers. One-view screening resulted in 542 recalls, 61 surgical biopsies, and 29 histologically proven breast cancers. The follow-up revealed 2 additional cancers detected by one-view screening. Thus, the use of two-view screening resulted in one more cancer case being detected. The difference in breast cancer detection was not significant.

Adult↗

Control of breast cancer through screening mammography.

There are more than 100 different malignancies that may develop in the human body. Unfortunately, very few of them can be controlled. Those we can control are not the most frequently occurring. Clinical research has made significant improvements in the past decades, attacking on all possible fronts: prevention, diagnosis/detection, and therapy. This overview article describes research results of the past 3 decades, demonstrating that early detection of breast cancer alters the natural history of the disease.

Breast Neoplasms↗

The present state of screening for breast cancer.

The results to date are convincing enough to justify recommending large scale mammography screening. The International Union Against Cancer (UICC) Workshop on screening for breast cancer in 1986 concluded that "In countries where breast cancer is common and where the necessary resources are available, screening using mammography alone or mammography plus physical examination is applicable as public health policy." The Swedish government has recommended screening with mammography for all women aged 40-74. This recommendation repeatedly emphasizes the necessity of high-quality examinations interpreted by well-trained radiologists. Screening with mammography is bringing breast cancer patients to therapy at a far earlier stage in the development of the disease. This calls for a re-evaluation of therapeutic methods.

Adult↗