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Biomedical subjects

L Tervilä

Publications and source records attributed to L Tervilä.

At least 19 recordsLinked to original sources
PubMed1983

Epicutaneous application of A2358 compresses containing ketocaine for pain relief in labor. A multicenter double-blind trial.

In the present multicenter trial 147 primigravidae were treated for low-back pain during the first stage of labor. 72 parturients were treated with A2358 compresses containing ketocaine, which were applied to the sacral lower-back region for one hour, 75 parturients were treated identically with compresses without the anesthetic drug. The pain relieving effect was almost the same in both treatment groups. The low-back pain was alleviated in about half of the mothers at 0.5, 10 and 1.5 hours after the application of both A2358 or control compresses. Supplementary analgesics had to be administered in about 60% of the parturients in both groups. The results show that factors other than ketocaine are involved in pain relief after application of A2358 compresses.

Adult↗
PubMed1982

Umbilical cord cortisol and arterial pH levels in spontaneous and induced labors.

The free cortisol concentration in umbilical cord plasma and the pH of umbilical artery blood were determined in 108 full-term fetuses delivered vaginally. Eighty-six of the labors were spontaneous and 22 were induced with oxytocin. The cortisol values correlated significantly with the pH values (r = -.608, P less .001). The cortisol values averaged 0.73 +/- 0.48 mumole/liter in the spontaneous labor group and 0.65 +/0 0.42 mumole/liter in the induced labor group. No statistically significant differences (P greater than .05) in the cortisol and pH values emerged between the groups. The results indicate that the human fetus reacts readily to intrauterine hypoxia and acidosis with endogenic cortisol secretion in both spontaneous and induced labors.

Female↗
PubMed1981

Intrapartum stress lowers the concentration of high density lipoprotein cholesterol in cord plasma.

The concentration of cord plasma triglycerides, total cholesterol, high density lipoprotein (HDL) cholesterol, and apoprotein AI and AII has been measured in acidotic and non-acidotic full-term neonates without chronic maternal-fetal problems. The level of cord plasma triglycerides was significantly increased (P less than 0.05) and that of HDL cholesterol significantly decreased (P less than 0.001) in the newborns belonging to the quintile class with the lowest blood pH (less than or equal to 7.20). No differences were present between the acidotic and non-acidotic neonates in the plasma concentrations of total cholesterol or of apoprotein AI and AII. The concentration of triglycerides was increased (P less than 0.05) and that of HDL cholesterol was decreased (P less than 0.05) in the infants with the longest duration of labour. No correlation was observed between the concentration of glycerol and lipids or lipoproteins in cord plasma. The results suggest that intrapartum stress raises plasma triglycerides and induces qualitative and quantitative changes in the plasma high density lipoprotein fraction in the newborn.

Cholesterol↗
PubMed1975

Acid-base relationship between mother and fetus in gestosis (pre-eclampsia) and in pregnant women with a labile blood pressure.

Simultaneous blood microsamples were taken from the maternal ear and uterine cervix and the fetus of healthy pregnant women, those with labile hypertension, and those with severe gestosis (pre-eclampsia). The po2, pH, BE and pco2 were studied. The fetuses showed no signs of asphyxia. The differences in BE values between the women withe gestosis and their fetuses were significantly greater than in the cases of healthy pregnancy. No differences were seen between healthy and gestotic gravida groups in po2, pH and pco2 values. This favours the opinion that in gestosis of the mother the fetus has a tendency to metabolic acidosis, which apparently places it in a poorer position than the fetuses of healthy mothers, should acute asphyxia occur. At the time of study the po2 of the fetuses of gravidas with a labile blood pressure was lower than that of fetuses of healthy gravidas.

Acid-Base Equilibrium↗
PubMed1975

Headache as a symptom of endometriosis externa.

Prior to an abdominal operation, 125 patients were asked if they regularly had headache during the menstrual period together with or without pain in the lower pelvic region. Pelvic pain patients with endometriosis externa reported headache significantly more often than those without endometriosis. Headache proved to be almost as common a symptom as lower pelvic pain in patients with endometriosis.

Adult↗
PubMed1975

Cerebral birth injury as a cause of epilepsy.

The possible role of cerebral birth injury in the aetiology of epilepsy was evaluated by comparing the birth histories of 101 epileptic patients with focal seizures and 208 with non-focal seizures. The former were smaller at birth and their mothers were older and had higher blood pressures than the mothers of the latter. Although the two groups did not differ significantly with regard to the frequency of breech birth, assisted vaginal breech deliveries were significantly more numerous in the focal group. The injured half of the brain was as often pressed against the sacrum as against the symphysis during birth.

Adult↗