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Biomedical subjects

L Tessari

Publications and source records attributed to L Tessari.

36 records · Page 2Linked to original sources
PubMedDate not supplied

[The blood calcium error induced by oral calcium loading: study of the homeostatic compensation mechanism].

The oral calcium load test, originally proposed for evaluating the intestinal calcium absorption and the renal calcium leak triggers some endocrine and metabolic responses addressed to correct the "calcemic error" induced by the load. Besides the increased plasma calcium there are: plasma PTH drop, increment in the urinary calcium excretion and in the threshold of tubular phosphate reabsorption. These responses have been measured and reciprocally correlated in 9 young adults at different times after the oral calcium load. The responses can be assessed with high precision in clinical practice and are in agreement with the known physiological models. The oral calcium load test is proposed as a tool for studying in the osteopenic population in the individual's capacity of correcting the calcemic error induced by the load.

Adult↗
PubMedDate not supplied

[Reduction in parathormone secretion after oral calcium loading in osteoporotic adults].

The purpose of this study was to verify if a decreased inhibition of PTH secretion (abnormal suppressibility) in response to physiological increment of plasma calcium is present in patients with osteoporosis. The plasma concentration curve of intact PTH 1-84 following an oral calcium load (Pak) has been calculated in a selected population of 38 osteopenic patients (16 males and 22 females) and in a control group of 9 young healthy adults. All the patients included in this study a) had no past or present diseases and medications of potential influence on calcium homeostasis, b) showed a maximal calcemic response to the oral calcium load equal to that of the control group. PTH suppressibility was significantly smaller in the osteoporotic patients (-42% in males and -32% in females) than in the control group (-76%). This abnormal suppressibility of PTH is independent on sex and, in the females, also on postmenopausal estrogen deficiency. These results support the hypothesis that osteoporosis is associated to an altered secretory response of parathyroid glands maybe due to reduced sensitivity of the parathyroid cells to extracellular calcium.

Administration, Oral↗
PubMedDate not supplied

[A case of cutaneous disorders of the lower limbs due to lymphostasis in a patient with multiple sclerosis. Use of a dynamic phlebologic footboard].

Tessari hemo-phlebo-dynamic steps are a passive physiotherapy device which cause the "ankle pump" to work, thereby contributing to venous return in the lower limbs. These steps can be used in phlebology in disorders due to stasis affecting the lower limbs, in orthopedics in functional rehabilitation as preventive treatment in the case of sedentary activities.

Aged↗
PubMedDate not supplied

[A method for the in vivo measurement of the mineral content in an experimental animal].

Bone mineral content measurement is not as widely used in experimental conditions as in clinical practice because of the lack of adequate experimental methods. An in vivo measurement method of bone mineral content in the rat is here presented. Measurements were made at the proximal tibio-peroneal segment, which has a mainly trabecular structure, by means of single photon absorptiometry. The presence of the fibula, having cortical structure, has been shown not to affect the read values, which can be therefore attributed to the tibial metaphysis, having a mainly trabecular structure. Expressing mineral content values as a function of the measured bone diameter has proven useless. Limb repositioning on the instrument holding device is critical for the reproducibility of the measurement, but the latter is not affected by the repositioning method. Method reproducibility (depending on either the intrinsic instrumental error or the repositioning error) is 5-6%. This relatively low reproducibility of the suggested method does not prevent its use in the study of physiological and pathological variations of bone mineral content in rats, and of the means to influence it.

Absorptiometry, Photon↗
PubMedDate not supplied

[Effect of insulin on the activity of bone alkaline phosphatase in culture].

Diabetes and osteoporosis are linked. The question remains, however, as to whether insulin has any direct effect on bone formation. To test this hypothesis we have measured, as a marker of osteoblast activity, alkaline phosphatase (ALP) released by rat limb intact bones incubated in the presence and in the absence of physiological concentration of insulin. The results indicate that insulin significantly (p less than 0.012) increases ALP by a mean value of 48% (from 5.4% to 215%) over matched controls. We conclude that insulin has a direct stimulatory effect on osteoblast activity, and that in the absence of this effect, as in diabetes, bone loss might occur.

Alkaline Phosphatase↗
PubMedDate not supplied

[Repercussions of venous diseases on the osteoarticular system of the lower extremities].

Two centuries ago, a leading light of phlebology (J.-L. Petit) wrote, "When ulcers, located beside bones, have been present for more than one year, the bones rot". Today, on the basis of many anatomical and radiological studies, this statement can be modified as follows: bone lesions may occur even before the onset of an ulcer; their nature is very variable and they are certainly more extensive in long-standing phlebopathies. In legs presenting open ulcers for more than 5 years, bone lesions are nearly always present but may not coincide with the location of the ulcer; the changes occur in the same way and follow the same pattern in post-phlebitic ulcer and in essential varices. Within the legs, notable reciprocal potentially pathogenic relationships are set up between the joints and the veins. These are more marked in the distal section of the limb than in the proximal section. It is therefore essential that at the first phlebological consultation, particularly in the presence of serious cutaneous lesions, an in-depth investigation should be carried out of the functional state of the osteoarticular system in order to be able to combine treatment of the venous pathology with a correct restoration of the hemokinetic pump.

Bone Diseases↗
PubMedDate not supplied

[Canyon-varices. Consequence and cause of sclerous cellulitis and their treatment].

Cutaneous and subcutaneous sclerosis of venous origin ("hypodermite chronique" to the French and "indurated cellulitis" to the Anglo-saxons) is always created by a "varicose vein-canyon", which communicates with one or several inadequate perforating? Varicose vein-canyons, or rather the circulatory and hypertensive disturbances that they engender, are without doubt mainly responsible for chronic panniculitis. It is extremely important to inactivate them to bring about regression of the sclerosis. The various ways of tackling the problem are based on three different principles: --contrasting the reflux from varicose vein-canyons by external compression; --cutting only vertical long reflux, by ablation or sclerosis of the inadequate saphenous veins and the other proximal varicose veins; --adding to the suppression of the long reflux by interruption of short reflux in the legs. The author insists yet again on the value of the "Glauco Bassi hook method", for which panniculitis is a choice indication, either because is enables the largest of the varicose vein-canyons (the "Leonardo vein") to be reached easily (and sometimes even to remove a few centimeters by rolling around forceps introduced into two incisions ten millimetres long at the most), or because there are few alternatives for interrupting the leakage points, if "sunk" varicose-veins are involved.

Cellulitis↗
PubMedDate not supplied

[Patients' rights, being the fourth third of phlebology therapy. Tribute to Glauco Bassi].

Current social, cultural and ethnic patterns all have an influence on phlebology therapy. At the present time, the desire to improve the appearance of their legs is much stronger than before in subjects who have uncomplicated varicose veins. This must be taken into consideration. However, it should also be noted that "capillary phobias" are met with, and these are nothing more than neuroses due to lack of adaptation to present-day life and are certainly not curable by phlebology therapy. On the contrary, care should be taken not to practice "Utopian medicine" in chronic venous insufficiency by prescribing treatment that the patient cannot or does not want to carry out. For this reason, it is not sufficient to prescribe the most logical treatment; a careful examination should be undertaken of the patient's character, requirements, family circle and work, as well as the influence exerted upon him by current social behaviour. Above all, three observations should be made. Some patients undertake cures that are completely different from those prescribed by their phlebologist, since they still have faith in certain outmoded rules. Others put into practice fragments of medical knowledge that have been passed on by popular wisdom. Very often the case is met of post-phlebitis patients who are unable to put on and take off their support stockings and who are the victims of current social conditions which no longer oblige families to help their close relations.(ABSTRACT TRUNCATED AT 250 WORDS)

Chronic Disease↗
PubMedDate not supplied

[Endogenous thermotherapy in patients with prosthesis and metal implants].

The conditions where metallic implants may be exposed to metric and centimetric electromagnetic irradiation have been experimentally produced "in vitro". Irradiation doses equal to those currently chosen for human physiotherapy, induce temperature increases which seem to be well tolerated by muscular and connective tissues. Conditions of maximal temperature increase around the metallic implant are those where the relative position of the electrodes to the body segments never occurs in practice.

Cartilage, Articular↗