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L Tomaszewski

Publications and source records attributed to L Tomaszewski.

61 records · Page 4Linked to original sources
PubMedDate not supplied

[Alpha 1-antitrypsin as an endogenous marker of protein-losing enteropathies].

A novelty of the present studies is the use of alpha 1-antitrypsin (A-1--AT) as an endogenous marker of enteric protein loss. Enteric clearance of alpha 1-antitrypsin was determined in 10 patients with the symptoms of PLE, and in 6 healthy individuals. Alpha 1-Antitrypsin concentration has been assayed in single, random samples of feces collected from 42 patients and 12 healthy individuals (normal values: 1.31 +/- 0.72 mg/g of feces). Markedly increased enteric clearance and A-1-AT concentrations in single, random samples of feces have been found in patients with enteric lymphangiectasis, Crohn's disease, ulcerative colitis, and constrictive pericarditis, slightly lower in coeliac, chronic diarrhoea, nonspecific hemorrhagic colitis, esophagitis, lambliasis, hypogammaglobulinemia, Wiskott-Aldrich syndrome, Rendu-Osler-Weber syndrome, hepatitis in newborn, and Gilbert's disease. Statistically significant positive clearance has been noted (r = 0.997; p less than .001). A single assay of A-1-AT in feces is simple, repeatable, and sensitive technique in the diagnosis and evaluation of these diseases in which the symptoms of enteric protein loss are seen.

Adolescent↗
PubMedDate not supplied

[Indicators of the identity of aspirates from the oral cavity of newborn infants and the amniotic fluid: pH, protein levels and the activity of trypsin inhibitor].

The aim of the study was to establish the biochemical identity as regards pH, protein content and trypsin inhibitor activity between the aspirate from the various sites of the newborn oral cavity and the amniotic fluid. It has been found that only correctly collected aspirate from the oral cavity without any admixture of the subepiglottic or gastric content is identical with amniotic fluid. Measurement of trypsin inhibitor activity in the improperly collected aspirate with pH below 5 must not be performed. The examination of the correctly sampled aspirates from the newborn oral cavity could be a source of the new early information regarding survival and the clinical condition of the newborn.

Amnion↗