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Biomedical subjects

L Tsalikis

Publications and source records attributed to L Tsalikis.

9 recordsLinked to original sources
PubMed1992

Gingival health and salivary function in head and neck-irradiated patients. A five-year follow-up.

Gingival health and salivary gland function were evaluated for a period of 5 years in 14 patients who received head and neck irradiation for nasopharyngeal carcinoma (seven patients; total dose greater than 60 Gy, nasopharyngeal field) and Hodgkin's lymphoma (seven patients; total dose less than 50 Gy, "mantle" field). Plaque index (PII), bleeding index (BI), gingival recession (GR), whole saliva flow rate (WSFR), left parotid sialographic morphology, and salivary gland radioisotopic activity were assessed immediately before radiotherapy and annually thereafter. The nasopharyngeal group had perfect correlation between postradiation depression of WSFR and the sialographic and scintigraphic scores (R = -1.00 and -0.96, respectively). The degree of gland dysfunction correlated negatively with BI and the BI/PII ratio (r = -0.497) and with GR (r = 0.681). The same correlations were noted in the group with Hodgkin's lymphoma during the first 3 years of follow-up. However, recovery of parotid gland function (WSFR and scintigraphic scores) and morphology (sialographic scores) and return to the preradiation relation between WSFR and both BI/PII ratio (r = 0.75) and GR (r = -0.71) were noted in the fourth year. The differences between the nasopharyngeal and Hodgkin's lymphoma groups are attributable to the delineation of the radiation field employed in each group.

Adult↗
PubMed1991

[Gingivectomy].

The gingivectomy is the oldest surgical approach in periodontal therapy. During the centuries, the technique has been modified. Just at the middle of our century, gingivectomy was the most important surgical method in periodontal treatment. Indication for performance of the gingivectomy is the complete elimination of the periodontal pocket (gingival overgrowth/e.g. hyperplasia, subgingival caries, subgingivally located crown margins. The physiologic design of the free gingival margin by surgical means, gingivoplasty, must be taken under consideration. Depending on the long and painful healing for the patient, gingivectomy should be preserved for the indications above. Wherever possible, is recommended a flap procedure like the apically repositioned flap.

Anesthesia, Dental↗
PubMed1991

[Preliminary results in periodontal treatment with guided tissue regeneration].

The objective of the present clinical study was to evaluate the predictability of a treatment procedure (GTR) aimed at regenerating periodontal tissue. 34 patients and 103 teeth were selected for the investigation. All teeth included in the study exhibited advanced loss of periodontal attachment. The periodontal defects were associated with even and/or angular bone defects or, in the case of multirooted teeth, advanced loss of periodontal tissue support in the furcation area. The probing bone level (PBL) and the probing tissue level (PTL) of the diseased sites were recorded using a standardized procedure. Treatment included placement of a barrier membrane (e-PTFE, Gore-Tex) according to the GTR method. After a healing period of 4-6 weeks the membrane was removed in a second surgical procedure. The result of healing was evaluated immediately after membrane removal. A further measurement was carried out during a re-entry operation 9 months later. The measurements of the treated sites revealed that GTR therapy had resulted in a marked tissue gain of more than 60% (p less than 0.001). In 33 of a total of 34 furcation-involved molars treatment had resulted in complete closure of the furcation defect. In the light of the findings of the present clinical trial it may be suggested that GTR therapy is an effective and predictable means of improving prognosis for both single- and multirooted teeth. A definite evaluation, of course, will be possible with the results of the re-entry procedure.

Adult↗
PubMed1991

[Changes in the physical properties of Gingivamoll flexible gingival epithesis].

It was the purpose of this study to investigate variations in weight, volume, hardness, material density, adjustment and colour of Gingivamoll flexible gingival masks during a period of twelve months. Additionally, patients were inspected for potential infections of Candida albicans. Thirty-three gingival masks of nine patients were selected for the study. One third was placed into patients' mouths, one third was placed on stone models under room conditions and a third group was submerged under water. At baseline all gingival masks were examined and measured. For the first half of the year, measurements were recorded monthly and in the second half of the year at two months' intervals. Results showed a constant Shore-A hardness, volume and density. Gingival masks submerged under water kept their weight. The other masks, i. e. those placed into patients' mouths and those placed on plaster models, lost weight. Adjustment deteriorated at distal sites. Colour stability was not satisfactory. Tests for Candida albicans remained negative. It can be concluded that Gingivamoll flexible gingival masks can be used without serious problems for a period of twelve months.

Adult↗
PubMed1991

[The etiopathogenesis of periodontal diseases: the role of microorganisms. A review].

The microbiology of periodontal diseases as well as associations between certain microorganisms and types/stages of periodontal diseases are discussed and the ecology and the composition of the subgingival plaque are included in this discussion, too. Furthermore, the possible role of microorganisms associated with periodontal diseases, their pathogenic mechanisms and their virulence factors are treated in the present article. Periodic upsets of the host-parasite equilibrium seem to be responsible for the bursts of disease progression. Several plaque hypotheses (specific, non-specific, opportunistic) have been proposed as likely models to explain the nature of periodontal infections and diseases. However, none of these theories is widely accepted at the moment. Therefore, we suggest that further investigations concerning the complex bacterial interactions and the manner in which the host responds to the mass and the composition of the dental plaque must be carried out in the future.

Adolescent↗
PubMed1989

[A latex agglutination test for the rapid identification of periodontally pathogenic microorganisms in subgingival plaque. The preliminary results].

Latex agglutination tests (LA) have been evaluated for identifying periodontal pathogens. This preliminary study compared LA tests with indirect immunofluorescence (IF) for the rapid identification of A. actinomycetemcomitans, B. gingivalis, and B. intermedius in clinical subgingival plaque samples. A total of 58 sites from 12 patients suffering from advanced periodontitis, exhibiting recent attachment loss were examined before and after initial periodontal treatment. The results of the two examinations were pooled and a total of 116 sites were statistically evaluated. The overall agreement between LA and IF was 75.8% for black pigmented Bacteroides (BPB) and 74.1% for Aa. These results demonstrate the feasibility of LA as a rapid, inexpensive, and reliable tool for monitoring periodontal disease offered to the general practitioner.

Actinobacillus↗