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Biomedical subjects

L V Adamian

Publications and source records attributed to L V Adamian.

At least 37 records · Page 2Linked to original sources
PubMed1991

[Reproductive function after surgery of the horn of uterus in rats].

A model of tuboplasty with the use of biologic glues (FK) and microsuturing material was created in experiments with 63 rats. Clinically commercial fibrin glue Beriplast FK manufactured by Bering (Germany) and FK-1 (USSR) were used in 15 patients during various gynecologic operations. The patency of uterine horn anastomoses, the formation of adhesions and other changes at the site of anastomosis were assessed, as was the incidence of the resultant pregnancy. Clinically early control laparoscopy was carried out on days 4-5 after surgery. The results evidence the efficacy of FK in reconstructive surgery on the uterine tubes. Preliminary analysis of the clinical data has confirmed the experimental data.

Animals↗
PubMed1991

[Characteristics of surgical treatment of pathologic conditions of the cervical stump].

The paper gives the results of surgical management in 65 patients with cervical stump diseases. According to the pattern of the disease, 4 groups of patients were identified: 1) those with inflammatory diseases, 2) those with endometriosis, 3) those with myoma, and 4) those with prolapse of the cervical stump. Low-quality and inadequate suture material was found to be a cause of inflammatory diseases of the cervical stump. It is concluded that it is not expedient to use capron, lavsan, and silk to suture the cervical stump during supravaginal amputation of the uterus. Catgut, vicryl, debone were shown to be an optimal suture material. The practice of surgical management of patients with inflammatory diseases, endometriosis, cervical stump myoma and prolapse indicates that it is advisable to extend indications for uterine extirpation.

Adult↗
PubMed1991

[Functional evaluation of the effectiveness of experimental reconstructive and plastic operations on the uterine horns].

In the given experimental model, tubo-plastic surgery was done with the use of locally produced fibrin glue (Fk-1), and commercial product "Beriplast" (FRG). In the control group microsurgical technique was adopted in the uterine horn of rats. It was proved that Fibrin glue reduces the frequency of post operative adhesion formation in the area of anastomosis and the chance of pregnancy is increased in comparison to microsurgical techniques.

Animals↗
PubMed1990

[Use of fibrin glue in gynecologic operations].

Anastomosing of the uterine horns in 98 experimental rats has employed a fibrin glue FK-1 (USSR) and Beriplast (FRG) or microsurgical techniques in a control group. Intactness and sealing of the anastomoses and the incidence of pelvic adhesions were assessed at 5 minutes, 1 hour and 1, 2, 3, 4, 5, and 6 days following the operation. The fibrin glue Beriplast was used clinically in 6 patients during reconstructive-plastic operations. The results with seamless anastomosing of uterine horns in rats using the fibrin glue and preliminary clinical evidence suggests a high effectiveness of the glue in gynecologic reconstructive plastic surgery.

Anastomosis, Surgical↗
PubMed1990

[Experience with the use of the CO2 laser in reconstructive and plastic gynecologic surgery in patients with uterine myoma and endometriosis].

CO2 laser has been used during reconstructive plastic surgery for uterine myoma, endometriosis of various locations, and associated gynecologic conditions in 71 patients. Comparison in patients with uterine myoma who underwent conservative myomectomy with and without the use of CO2 laser showed that treatment with CO2 laser diminished blood loss and duration of the operation, and improved postoperative progress.

Adult↗
PubMed1990

[Combined treatment of retrocervical, cervical and vaginal endometriosis using CO2 laser, cryosurgery and electrocoagulation].

Clinical data and results of combined treatment have been analyzed in 163 patients with common types of endometriosis: retrocervical in 116, cervical in 43 and vaginal in 5 patients. Growth of retrocervical endometriosis into the vaginal wall with cyst formation was seen in 21 patients. Conventional surgical procedures were adjuncted by physical treatments of endometriosis foci or beds in 116 of 163 patients: electrocoagulation (n = 44), cryodestruction (n = 43), focal vaporization with a CO2 laser (n = 29). Only surgical methods with subsequent hormonal therapy were used in 47 patients who made a control group. The results showed that the additional cryo-, electro- and laser surgery considerably reduced the incidence of complaints and relapses. CO2 laser treatment had a significantly higher efficacy.

Adult↗
PubMed1990

[Surgical treatment of disseminated forms of external genital endometriosis using CO2 laser].

CO2 laser surgery has been performed in 56 patients with external endometriosis which had Stage III-IV dissemination according to the AFS classification (1979). A control group included 20 patients who were operated without using CO2 laser. Analysis of the major operative parameters, such as operation duration, blood loss, length of the postoperative period, febrile response, incidence of postoperative relapses suggested that the use of the laser technically facilitated surgery in patients with disseminated endometriosis, shortened the operation and was associated with a smaller intraoperative blood loss, better postoperative course, more reliable asepsis and ablastics and lower incidence of relapses.

Carbon Dioxide↗
PubMed1990

[Prospects of the use of neoplasm antigens as markers of gynecologic diseases].

CA-125 antigen was assayed in 108 patients with the most prevalent gynecologic diseases by enzyme immunoassay. Its blood levels were found to be under 35 U/ml in the patients with inflammatory diseases. In endometriosis and benign ovarian tumors CA-125 concentrations in the blood were elevated. Malignant tumors of the ovaries were detected in 80 percent of the examinees. CA-125 levels reduced after surgical treatment in 72 percent of patients. These data permit a conclusion that CA-125 diagnostic agent may be used to monitor the course of the postoperative period and assess the late results of treatment.

Adolescent↗
PubMed1990

[Anatomic and functional characteristics of resistant ovaries].

Resistant ovary syndrome has been confirmed in 42 women using clinical, roentgenologic (craniography, hysterosalpingography, pneumogynecography, electroencephalography), genetic, sonographic, endoscopic and histologic studies. Fibrocystic breast disease was identified in 64% and normal ovarian size in 74% of the patients with resistant ovary syndrome. Progesterone test was positive in 84% of the patients. Resistant ovary syndrome was associated with higher serum estradiol levels as compared with ovarian dystrophy and pure gonadal dysgenesis. Diagnosis confirmation requires ovarian biopsy with a histological examination of ovarian specimen, but its outcome is not always significant.

Adult↗
PubMed1990

[Alternative solutions in the treatment of patients with combined benign endometrial and myometrial pathology].

The study included 96 women with combined benign hyperplastic uterine conditions. Half of them underwent a radical uterine resection and were examined at 3.1 +/- 0.2 years following the operation. The rest were randomly selected as matched pairs and were evaluated at 4.3 +/- 0.13 years following multicomponent treatment including hormones (n-26) and cryohormonal treatment (n-22). Analysis of results revealed a complex pathogenesis of this disease of the reproductive tract, presenting as severe postoperative vegetoneurotic disorders. Potential of an adequate conservative treatment in preserving specific female functions was determined.

Adult↗