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Biomedical subjects

L V Adamyan

Publications and source records attributed to L V Adamyan.

5 recordsLinked to original sources

Minimally invasive surgery in gynecologic practice.

The medical world is facing increasing demands for improvement of the quality of life of women of all ages. This is not possible without overall improvement of the healthcare of females, and, in particular, of the quality of surgical treatment for gynecologic pathology. Positive changes are ensured by the active introduction of minimally invasive technologies into all spheres of gynecologic practices. There are almost no medical, demographic or technical limits for the application of endoscopy in gynecology, while the benefits it provides are extraordinary. The process of positive change towards minimally invasive surgery in operative gynecology should be supported and promoted by the medical community in every possible way.

Endometriosis↗

Comparative effects of different methods of anastomosis on rat uterine horn.

This study compares the results of microsurgical uterine horn anastomosis performed using fibrin glue (FK-1), 8/0 Prolene sutures, or fibrin glue in combination with 8/0 Prolene sutures. Thirty-two rats were divided into three groups. Three results were studied: frequency of adhesion formation in the area of anastomosis, uterine horn patency, and pregnancy rates. Compared with microsurgical sutures, fibrin glue used for the anastomosis of uterine horns in rats results in identical pregnancy and patency rates. Moreover, the formation of adhesions was significantly lower and the duration of surgery was shortened.

Anastomosis, Surgical↗

Use of fibrin glue in obstetrics and gynecology: a review of the literature.

Most authors consider the principal advantage of FG anastomoses (compared to microsurgical anastomoses) to be shorter operating time, reduced surgical trauma to oviduct stumps, and absence of tissue ischemia. These features promote reparative regeneration and decrease adhesion formation, resulting in complete recanalization of fallopian tubes. To date, the majority of work on FG is confined to the experimental development of surgical techniques. Investigations in reconstructive gynecological surgery are quite uncommon. The physical properties of FG and the positive results of available experimental studies suggest that further development of surgical techniques using FG in obstetrics and gynecology is worthwhile.

Fibrin Tissue Adhesive↗

Reproductive function after reconstructive surgery on rat uterine horns.

OBJECTIVE: To assess the effectiveness of tuboplasty procedures employing fibrin glue. METHODS: Experimental tuboplasty operations were performed on 63 rats using biological glues (fibrin glue--"Beriplast" Behring; "FK-1", Russia) and microsuture materials. Uterine horn patency, adhesion formation, and other changes at the site of anastomosis, as well as pregnancy rate and embryonal characteristics, were assessed. CONCLUSIONS: We confirmed the effectiveness of fibrin glue application in reconstructive surgery on uterine horns, and documented no significant differences between microsuture and sutureless anastomoses with regard to pregnancy rates (80 and 83.3%, respectively).

Animals↗

Hormonal and immunologic methods in the diagnosis and treatment of patients with benign ovarian tumors and endometriotic cysts.

OBJECTIVE: To compare efficacy of various methods for characterizing endometriosis and benign ovarian tumors. DESIGN: Two parallel groups of patients, 54 with endometriotic ovarian cysts and 48 with benign tumors. SETTING: Central clinic. PATIENTS: Patients referred from all regions over a 5-year period. OUTCOME MEASURES: Estrogen Estrogen and progesterone receptor levels of endometrium and endometriotic foci, CA-125 concentration, and estradiol, progesterone, LH, and testosterone blood levels. RESULTS: LH levels elevated during follicular phase in patients; estradiol levels reduced; receptor levels abnormal in endometriosis, but not in benign ovarian cysts. CONCLUSIONS: Hormone therapy is adequate treatment for endometriotic cysts. CA-125 is not a reliable indicator for differential diagnosis.

Antigens, Tumor-Associated, Carbohydrate↗