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Biomedical subjects

L V Demidova

Publications and source records attributed to L V Demidova.

At least 19 recordsLinked to original sources

[Present trends in the development of radiotherapy].

New potentialities of radiotherapy of cancer patients are associated with three scientific directions: investigations in clinical radiology, the use of advantages of radiation advanced technology and guarantees of therapeutic quality. The first direction includes scientifically substantiated regimens of non-classic dose fractionation, various radiomodifiers and their combinations, and individual prognosis of a tumor response to ionizing radiation. This direction based on 3000 cases, holds promise. The second direction is associated with the advantages of modern technology used for diagnosis, topometry and radiotherapy design. The third direction is intended to reduce differences in radiotherapy quality between research institutes and cancer hospitals.

Humans↗

[Prospects of development of radiotherapy in an oncological clinic].

It is believed that new anticancer potential of radiotherapy lies in further research efforts in the fields of: clinical radiobiology, utilization of the last developments in radiological equipment, overall high quality of radiological service. Research in radiobiology should be aimed at the design of nonstandard dose fractionation, introduction of various modifiers and their combinations, prediction of individual responses of the tumor to ionizing radiation. First-hand clinical data on 3000 cases support the promise of such approach. The advantages of modern equipment could be successfully realized at the stage of confirming the diagnosis and topography++, design of the treatment schedule and in the process of radiotherapy. To warrant the same quality of radiological service rendered in large cancer research centers and provincial hospitals, the latter should be provided with relevant equipment, methodological instructions, participate in current cooperative programs.

Cancer Care Facilities↗

[Relation of the levels of thyroid hormones and cortisol and the degree of systolic arterial pressure in 11- and 12-year-old boys].

An epidemiologic evaluation of relationships between arterial BP changes, and thyroid and adrenocortical hormones was carried out in eleven- and twelve-year-old boys. Different patterns of correlation were demonstrated between plasma thyrotropic hormone, thyroid hormones and cortisol levels, on one hand, and systolic BP variation, on the other. There was a correlation between thyroid hormones and cortisol in these groups. The results suggest that even slight changes in thyroid and adrenal function may promote disorders of BP regulation.

Age Factors↗

[Radiotherapy of cancer of the stump of the cervix uteri].

The paper is concerned with the results of combined radiotherapy provided to 68 patients with cancer of the cervix uteri stump. An impossibility of homogenous irradiation of the whole affected organ due to its anatomic specificities during intracavitary gamma-therapy following the prior supravaginal amputation of the uterus results in a dose deficiency in the cupola of the cervix uteri stump which should be made up for by gamma-beam therapy. It makes it possible to achieve the 5-year survival in 81.8% of patients.

Adult↗