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Biomedical subjects

L V Klimova

Publications and source records attributed to L V Klimova.

6 recordsLinked to original sources
PubMed1991

[Immunologic indices in chronic pancreatitis and in its combination with other diseases of the digestive system].

Analysis of the immune system status of 200 patients with chronic pancreatitis has shown more marked immune shifts in the patients with the primary condition, who presented with high levels of immune complexes and autosensitization to pancreatic tissue. When pancreatitis was associated with intestinal abnormalities, T lymphocyte function was depressed, as was nonspecific defense of the body. In cases when chronic pancreatitis resulted from diseases of the bile duct, stomach, or duodenum, the findings evidenced high blood serum levels of immunoglobulins A, G, and M, and significant bacterial sensitization. These results may be useful in choosing immunocorrecting therapy.

Chronic Disease↗
PubMedDate not supplied

[The characteristics of the diagnosis and clinical picture of pseudotumorous chronic pancreatitis].

As many as 12 patients with pseudotumorous chronic pancreatitis have been examined. While studying the functional state of the pancreas a conclusion was reached about a decrease in the organ's exocrine activity, with the hormone output remaining unaffected. Particular features of the immunity status in the patients are outlined. It is recommended that dynamic ultrasonic investigation and computerized tomography to the abdominal cavity and retroperitoneal space, transcutaneous puncture biopsy of the pancreas, should be used for the differential diagnosis with carcinoma of the organ to be made possible.

Chronic Disease↗
PubMedDate not supplied

[The diagnostic significance of soluble fibrin monomer complexes in exacerbated chronic recurrent pancreatitis].

The authors theoretically explain the elevation of blood plasma levels of soluble fibrin monomer complexes occurring in elevated trypsin concentrations in the blood. Examinations of 50 patients with chronic relapsing pancreatitis and of 20 donors demonstrated a marked correlation between the levels of immunoreactive trypsin and soluble fibrin-monomer complexes in the blood. The authors recommend measurements of blood soluble fibrin-monomer complexes for the diagnosis of exacerbations of chronic relapsing pancreatitis.

Chronic Disease↗