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Biomedical subjects

L V Lysenko

Publications and source records attributed to L V Lysenko.

11 recordsLinked to original sources
PubMed1998

[An exogenous psychotraumatizing factor as one of the causes for the development of neurotic reactions in subjects suffering from sensorineural hypoacusis].

We performed special psychological investigations in 120 patients with neurosensory hypoacusis (NSHA) and emotional somatovegetative disorders. These patients were found to have neurosis and neurosis-like conditions. To elucidate the involvement of the exogenic factor on the onset of neurotic reactions in NSHA, we performed a questionnaire survey reflecting the attitude of the family, coworkers, strangers to people with hearing problems. It was found that neuroses and neurosis-like conditions in NSHA patients are provoked not only by premorbid personality traits but also by exogenic psychotraumatic factors.

Adolescent↗
PubMed1990

[Diabetic macro- and microangiopathy of the lungs].

Results of histologic, immunohistochemical and ultrastructural examination of pulmonary vessels of 85 necropsy cases (65 patients had diabetes and 20 were controls with atherosclerosis). In the lung vessels in diabetes the changes in the arteries of the elastomuscular and muscular types were frequently found (73.8 and 81.5%, respectively) which were regarded as manifestations of diabetic macroangiopathy, as well as those of arterioles, capillaries (81.5 and 55.4%, respectively) which are the expression of diabetic macroangiopathy. Macroangiopathy is represented by thickening of the endothelial basal membrane, destruction of the internal elastic lamina, its mucoid edema. An extreme manifestation is lipogranulomatosis of the arteries of muscle type. These changes are frequently associated with arterial thrombosis. Diabetic microangiopathy is characterized by plasmorrhagy and hyalinosis of the wall (lipohyaline) with the development of the nodular arteriolo-hyalinosis, the thickening of the endothelial basal membrane and frequent necrosis of capillary pericytes. A specific feature of the diabetic angiopathy is lipidosis of all cells in the lung artery system and its extracellular structures combined with lipidosis of type II pneumocytes producing surfactant and phagocyting alveolar macrophages and polinuclear leukocytes.

Adult↗
PubMed1990

[Ultrastructural and ultracytochemical changes in the lungs of rats with diabetes mellitus].

Diabetes mellitus was produced in Rats by means of a single streptozotocin injection. The evolution of the lung ultrastructure and of the state of the alveolar epithelium glycocalix was followed during two months. Among the different cellular types of the lung parenchyma, the main alterations were revealed in the pneumocytes of type II. They consisted in severe enlargement of the endoplasmatic rough net channels, diminution of the quantity of the lamellated corpuscles and delay of their output out of the cytoplasm, the reduction of microvilli and thinning of the glycocalix. As an answer to the epithelium alteration, a regeneration of the type II pneumocytes was discovered. A structural insufficiency of the phagocyte system--polymorph nuclear leucocytes and alveolar macrophages was noted.

Animals↗
PubMed1982

[Changes in the lungs in diabetes mellitus].

Morphological examinations in the lungs in patients with diabetes mellitus of different degrees of severity and duration (28 autopsy observations) were carried out. Diabetic microangiopathy in the lungs was found to involve the capillaries of alveolar septa and arterioles as well as pleural arterioles, and is manifested by plasmorrhagia, insudation, thickening of basal membranes and hyalinosis of the vessels. Moreover, intraseptal nodules, granulomas in small artery walls, focal proteinosis develop in the lungs followed by sclerosis of the microcirculatory bed vessels and centrilobular emphysema. All these comprise a favourable background for the development of pneumonias which, along with pulmonary-cardiac insufficiency are one of the most frequent causes of death of patients with diabetes mellitus.

Aged↗
PubMed1979

[Morphological changes in the lung blood vessels in diabetes mellitus].

Examinations of the lung vessels in diabetes of various degrees of severity and duration revealed changes in the vessels similar to diabetic microangiopathy in other organs (kidneys, skin). Manifestations of diabetic microangiopathy in the lungs are most marked in arterioles and capillaries of the alveolar septae. Diabetic microangiopathy in the lungs is characterized by phenomena of plasmorrhagy and insudation, thickening of capillary basal membranes, sclerosis and hyalinosis of capillary and arteriola walls, and accumulation of alveolar macrophages resorbing metabolism products in alveolar lumen. Diabetic microangiopathy leads to the development of alveolar septae sclerosis and to centrilobular pulmonary emphysema. As compared with the involvement of the vessels in the kidneys and the skin, manifestations of diabetic microangiopathy in the lungs lag in their development and are less manifest.

Aged↗
PubMedDate not supplied

[The role of Pathology Department of the I.M. Sechenov Moscow Medical Academy in the development of forensic medicine].

The chair of pathology has greatly contributed to establishment and development of prosector's speciality: training of pathologists, initiation of first clinico-anatomical conferences and their upgrading, introduction of novel morphological techniques and other advanced methods, publication of books, guidelines, manuals. The chair, A. I. Abrikosov and I. V. Davydovsky especially, contributed much to transformation of the pathology service in Russia after 1917.

Forensic Medicine↗