Biomedical subjects
Publications and source records attributed to L V Peshkova.
An investigation was made of fundamental biophysical principles of the intrinsic electric system functioning in different conditions. This system was shown to govern the vital functions of separate cells and of the entire live organism. We developed a method enabling the correction of an affected intrinisic electric system. This method is based on the application of an external electric current.
The content of K+ was evaluated in erythrocytes of the blood collected from the finger and gingiva of normal people and patients with parodontosis. The content of K+ in erythrocytes of the capillary blood was discovered to increase with the enhancement of the disease severity. The permeability ratio for K+ did not essentially change. The data obtained confirm the suggestion that parodontosis is a systemic disease rather than a local affection.
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Seasonal changes of the constant electric field of healthy people of various age groups were studied. The constant electric field was shown to be characterized by a fine structure of distribution of electric potential differences (EPD) along the skin in relation to a referent point located on the neck in the intersection region of trapeziform and clavicular-nipple muscles. The constant electric field of the people of all ages undergoes seasonal changes involving displacement of all EPD values to the positive region during autumn-winter period as compared to the spring-summer one. It is suggested that such EPD change is conditioned by a change of the organism metabolic activity. The discovered differences in EPD displacement values of various age groups can serve as physiological characteristics of transitional processes in the growing organisms.
Fine structure of distribution of electric potential difference (EPD) in human skin of some points on arms, body and face relative to a referent point on the neck was investigated. Diurnal variations of EPD fine structure for individuals and seasonal differences expressed in an increase of the amplitude of variations and shift of EPD mean values to the positive region in winter as compared with summer were observed. The indicated peculiarities are connected with external factors and reflect changes of metabolic activity of organism living activity processes.
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The ATP hydrolysis by homogenates of oral cavity mucosa, parotid, mandibular and sublingual glands of rats was studied depending on the animal age (1,3 and 12 months). In all the studied tissues the souring of incubation medium due to ATP hydrolysis is followed by its subsequent alkalization up to the initial pH. The alkalization rate increases with the animal age and by 12 months reaches its constant value (within 22.5 +/- 4.1-25.7 +/- 7.5 ng-ion H3 per 1 mg of protein for 1 min). The observed effect evidences for an increase in the mitochondrial membrane permeability of the studied tissues with the animal age.
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Explore the source record for details and available documents.