PubMed Health⌕ Search

Biomedical subjects

L V Poluéktov

Publications and source records attributed to L V Poluéktov.

At least 19 recordsLinked to original sources
PubMed2002

[Local sorption-detoxication therapy in combined treatment of acute purulent paraproctitis].

Efficacy of sorption-detoxication therapy (sorbent SUMS-1) in combined treatment of acute purulent paraproctitis was evaluated. Degree of endotoxication, state of postoperative wound, structural and morphological state of mucosous membrane of the rectum (light, electron microscopy, morphometry of biopsies) were studied. It was found that local use of sorbent increases efficacy of treatment of severe paraproctitis: endotoxicosis eliminates, regional hemo- and lympho-circulation improves, wound regeneration activates.

APACHE↗
PubMed1989

[Adaptation reactions in acute peritonitis and their correction using sorption detoxification].

Examined were 233 patients with acute peritonitis. In patients, who underwent the conventional intensive infusion therapy alone, in complicated course of the postoperative period, within 28 days, the high level of pathologic stress reactions was observed, which correlated with changes in the content of middle molecular mass peptides (MMMP). In uncomplicated course of the postoperative period, the MMMP level and adaptation reactions didn't differ from the control findings. Hemosorption in patients with high toxin level was accompanied by the decline in MMMP concentration below the diagnostic level, restoration of physiologic adaptation reactions.

Acute Disease↗
PubMed1989

[Immunologic reactivity and sorption detoxication of patients with acute peritonitis].

Follow-up using immunological monitoring of 233 acute peritonitis patients revealed various immunological shifts occurring at all levels postoperatively, with the therapeutic methods being common. Depression of specific immune response mechanisms (T- and B-systems) along with disinhibited phylogenetically old forms of the common biological phenomenon non-specific immunity (phagocytosis) is believed to reflect the common adaptive mechanism activated in emergencies in patients with peritonitis. With high levels, the toxin median molecular mass polypeptide in the complicated postoperative course, the immunological impairment is more pronounced, while restoration of immunological responsiveness of the organism becomes protracted, resulting in reduction of the cellular homeostasis and metabolism reserved. Application of the extracorporeal detoxication-hemosorption promotes adaptation buildup and makes immunity functioning optimal.

Acute Disease↗
PubMed1985

[Insulin-depositing function of peripheral blood erythrocytes in rats that have sustained severe craniocerebral injury].

Rats with a grave craniocerebral injury were examined over time for the content of insulin in red cells (1, 3, 7, 14, 21 and 35 days after injury). Alterations were found in the affinity of circulating red cells for paraaldehyde fuchsin (PAF), linked primarily with a decrease in the proportion of the PAF-resistant forms of the cells. It is suggested that in general the data obtained reflect the intensification of the receptor function of the red cell membrane.

Acute Disease↗
PubMed1983

[Use of the antioxidant ionol to prevent damage to the heart from prolonged administration of antitubercular preparations].

Prolonged administration of isoniazid, protionamide and rifampicin to white rats is accompanied by marked depression of myocardial contractile function determined by the distress of membranous mechanisms of calcium transport because of excessive activation of lipid peroxidation in cardiomyocyte biomembranes. Administration of ionol coupled with antituberculous drugs prevents their cardiotoxic effects.

Animals↗
PubMed1981

[Stereologic analysis of myocardial ultrastructure during the postresuscitation period].

The myocardium of dogs which suffered the 5-minute clinical death was subjected to ultrastructural stereologic examination. It was found that the T system density volume in cardiac myocytes was drastically reduced because of the massive destruction of its tubules. The regeneration of the T system was slow in progress. The mitochondrial density volume was discovered to be reduced 6 hours after the resuscitation. The myocardial ultrastructure virtually returned to normal by the end of the second week of the postresuscitation period.

Animals↗
PubMed1980

[Intraoperative peroral gastroduodenoscopy].

Gastroduodenoscopy when performed during laparatomy because of the difference between preoperative and operative diagnosis allows to obtain additional objective data on the pathological process and to solve the question of the further surgical tactics. It may be used for diagnosis of the proceeding hemorrhage from the anastomosis suture and for revealing defects of the operation technique.

Adult↗