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Biomedical subjects

L V Potashov

Publications and source records attributed to L V Potashov.

At least 91 records · Page 5Linked to original sources

[Regeneration of the gastric mucosa under conditions of massive blood loss].

The autoradiographic method was used for a comparative study of regeneration of the gastric mucosa after wounding the rat with a preliminary loss of blood and without it. The H3-thymidin label index was determined in the portions of the mucosa of the wound edge and far from it. A histological analysis of healing the wounds failed to reveal any difference in terms of this process in rats with a loss of blood and without it. A momentary massive loss of blood did not influence the strain and intracellular regeneration processes in the healing wound of the stomach: the amount of cells synthesizing DNA at the edges of the gastrotonic wound proved to be the same in experiments both with a loss of blood and without it. The authors believe that it may serve as an indirect evidence of a somewhat exaggerated danger of surgery at the height of gastroduodenal bleeding.

Animals↗

[Evaluation of the hazard of surgical intervention at the height of gastroduodenal hemorrhage].

Based on the experimental data obtained, it was concluded that the danger of surgery at the height of the primary hemorrhage, although massive it may be, is somewhat exaggerated by surgical specialists. Recurrent in a short period of time hemorrhages are believed to be more inherent in danger than an operation in primary bleeding. The results of the experiments are supported by observations over 70 patients, operated upon for ulcerous bleeding, and in 11 patients who were subjected to surgery for profuse hemorrhage from cancerous gastric ulcers.

Aged↗

[Bone marrow reaction to surgical intervention in gastroduodenal hemorrhage].

Experimentally and clinically, the authors have studied the effect of massive blood loss and various operative procedures (Billroth I and Hofmeister-Finsterer gastrectomies, pyloroplasty with vagotomy) on the hemopietic system. It has been found that the bone marrow response was mainly dependent on blood loss. A surgical intervention renders but insignificant effect on hemopoiesis, similar to that of a moderate hemorrhage, the character of an operative procedure being of no improtance.

Adaptation, Physiological↗

[The efficacy of the ultraviolet irradiation of the blood in the combined treatment of erysipelatous inflammation].

An experience with treatment of 1527 patients with different forms of erysipelas is analyzed. Under study were clinical data, nonspecific resistance parameters, peripheral and central hemodynamics and viscosity of blood. Ultraviolet irradiation of blood is an effective method of pathogenetical treatment of erysipelas which results in rapid arrest of local and general symptoms of the disease. The number of complications and recurrences was reduced.

Adult↗

Surgical treatment of chronic ischemia of the digestive organs caused by compressive stenosis of the celiac trunk.

Compressive stenosis of the celiac trunk is a common cause of chronic ischemia of the digestive organs with consequent morphological and functional changes in these organs. Decompression of the celiac trunk is an effective operation which normalizes the central and visceral circulation and results in resolution of ischemic lesions of the digestive organs and cicatrization of ischemic gastroduodenal ulcers, in particular. In some cases it is necessary to combine decompression of the celiac trunk with other surgical procedures to eliminate complications of ischemic lesions of the stomach and duodenum or other associated lesions.

Adolescent↗

[The association of HLA antigens with gastric and duodenal peptic ulcer].

The association of duodenal ulcers with antigens AIO and combinations of antigens B18B40, B35B40, A10B5, A10B40 and others and the association of gastric ulcer with antigens A3B7, A3B40, B14B15 were revealed by an investigation of HLA antigens in 46 patients with ulcer disease of the duodenum and 25 patients with ulcer disease of the stomach. It was concluded that the ulcer disease had a hereditary predisposition characterized by genetic heterogeneity with different etiopathogenetic mechanisms of the development of ulcers of different localizations. The HLA antigens may be used as immunogenic markers of ulcer disease if observing the population method in the investigations.

Adolescent↗