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Biomedical subjects

L Valdés Cuadrado

Publications and source records attributed to L Valdés Cuadrado.

5 recordsLinked to original sources
PubMed2006

[COPD, a public health problem].

The fundamental etiologic factor of COPD is tobacco. This has a 9% prevalence in Spain and although this rate is underestimated according to the last studies, COPD generates about 39,000 hospital admissions per year. It has a re-admission rate between 12% and 32%, infections being the fundamental cause. The average care cost per patient from its diagnostic to death is 27,500 euro and we should add a high percentage of employee absenteeism. Due to its chronic aspect, high health care cost and possible improvement of the quality of life of patient, the solution to the problem needs to have a more active involvement of the doctor who attends these patients.

Humans↗
PubMed1989

[Comparative study of the bronchodilator effect of inhaled fenoterol and aerosol salbutamol in patients with chronic bronchial asthma].

The bronchodilator effects of inhaled fenoterol (FI) and salbutamol aerosol (S) in 15 patients (8 male and 7 female with a median age of 44 +/- 13 years), diagnosed as suffering from asthma, were studied using spirometry (determining FEV1, FEF 25-75% and FVC) and flow volume curves (PEF, MEF 75% and MEF 25%). The mean theroric rate of FEV1, PEF, MEF 75% was defined as the theoric rate of the obstruction of central airways (PCA%) and the mean of FVC, FEF 25-75% and MEF 25% rates defined as the rate of the theoric obstruction of the peripheral airways (PPA%). Basal and 5, 15, 30, 60, 120, 240, 360, 480 minute determinations were done, after the administration of 200 mcg of S in the conventional way on two different days. The statistic study carried out using the "u" test of Mann-Whytney. No statistically significant differences in intensity, onset nor duration of the effect between both drugs were found. We concluded that FI is a drug of great utility in treatment of asthmatic patients and one which allowed, because of the easy inhaling technique, the use of beta 2 adrenergic drugs in a mayor number of patients who would otherwise have to resort to an alternative form of administration.

Administration, Inhalation↗
PubMed1989

[An endobronchial mass as the presentation of tuberculosis. A report of 3 cases and review of the literature].

3 cases of endobronchial TB are described. They were diagnosed as endobronchial mass which deviated the diagnosis to another pathology in absence of sputum culture. The TB treatment produced a complete resolution of the lesions. We highlight the endobronchial mass as a non-frequent clinical feature of EBTB and we should bear this etiology in mind in differential diagnosis of all endobronchial masses even if the clinical and endoscopic data are of bronchial tumor.

Adolescent↗
PubMed1989

[The usefulness of cholesterol determination in the etiology of pleural effusion].

95 pleural effusions of different etiology were studied. 25 were transudate, 22 neoplastic, 28 caused by tuberculosis, and 20 miscellaneous. The Light parameters (pleural protein/plasma) (Prot LP/P), Pleural LDH (LDH LP) and LDH pleural/plasma quotient (LDH LP/P) were determined and compared with the efficacy of pleural cholesterol (Chol LP) and pleural cholesterol/plasma quotient (Chol LP/P) to differentiate the transudate from pleural exudate. With Prot LP/P quotient the sensitivity was of 85% and the specificity 91.6%; with LDH LP the sensitivity was of 74.6% and the specificity 97.6%. With the LDH LP/P quotient the sensitivity was of 89% and the specificity 87.8%. The sensitivity of each parameter was similar to that obtained by Light but less specific. All the transudates had levels of chol LP lower than 55 mq/dl (100% specificity) with a sensitivity of 84%. The Chol LP/P quotient had a limit of 0.3, this being its sensitivity of 91.3% and 93.1% its specificity. The presence of both parameters were necessary to the classification and the sensitivity obtained being of 80.3% and the specificity 100%. We concluded that the determinations of Chol LP and the Chol LP/P quotient are of great advantage in differentiating the pleural transudate from pleural exudate and the predictive value is, at least, similar to that obtained by Light.

Adult↗