Biomedical subjects

L Vicari

Publications and source records attributed to L Vicari.

20 records · Page 2Linked to original sources

PubMedDate not supplied

Trisomy 4 and ring chromosome in a patient with acute myelomonocytic leukemia.

We describe a patient with acute myelomonocytic leukemia (AMML) in whom cytogenetic analysis revealed trisomy 4 associated with a ring chromosome. In addition, in a cytogenetically unrelated clone, trisomy 8 and 5q- abnormalities were detectable. The possibility of a subclinical myelodysplastic syndrome preceding the onset of AML is discussed on the basis of the morphological and cytogenetic findings.

Aged↗

PubMedDate not supplied

Trisomy 13 in a case of myelofibrosis with myeloid metaplasia with early blastic transformation.

We describe a case of early myeloid blastic transformation in a 64-year-old man suffering from myelofibrosis with myeloid metaplasia. Both chronic and blastic phase cytogenetic analysis showed trisomy 13 to be the sole chromosome aberration. A potential role for this rare abnormality in determining such an unusually poor clinical outcome is discussed.

Blast Crisis↗