PubMed Health⌕ Search

Biomedical subjects

L W Nolte

Publications and source records attributed to L W Nolte.

3 recordsLinked to original sources

Signal detection theory and reconstruction algorithms--performance for images in noise.

In many noisy image processing situations, decision making is the ultimate objective. In this paper, we show using signal detection theory how direct optimal processing of the projection data yields a considerable gain in the decision making performance over that obtained by first using image reconstruction. The problem is formulated in the framework of a two hypotheses detection problem. Optimal processors based on the likelihood ratio approach have been presented for two cases. The first considers direct processing of the projection data. The second applies optimal decision theory to the reconstructed data. Results based on computer simulation are presented in the form of receiver operating curves (ROCs) for different signal-to-noise (SNR) ratios. Early results indicate that large performance gains can be achieved by direct optimal processing of the projection data compared with optimal processing of reconstructed data. Results for the latter case can be interpreted as providing an upper bound on all postreconstruction decision rules. We hope to extend this approach to a number of different aspects of the image decision making problem.

Algorithms↗

CNR enhancement in the presence of multiple interfering processes using linear filters.

Given several images of the same slice, a linear filter can produce an image in which the contrast-to-noise ratio (CNR) between pathological and normal tissues is greater than in any of the initial images. To distinguish the pathology from more than one tissue, the filter should optimize the set of CNRs between the pathology and each of the interfering tissues. We define the optimal filter as the one which provides the largest value for the minimum CNR in the set and show how it is selected from a field of only four possibilities. The filter is demonstrated with both experimental phantom studies and clinical cases. Filter performance is compared with that of other techniques for distinguishing a desired feature from more than one interfering process.

Image Enhancement↗