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Biomedical subjects

L Wille

Publications and source records attributed to L Wille.

At least 55 records · Page 3Linked to original sources

[Transporation of high-risk new borns (author's transl)].

Organisation and results of a mobile intensive unit for high-risk neonates are reported. Within one year 134 transporations were required. Temperatures of the incubator from the beginning and the end of the transports as well as body temperature, blood gas analysis and blood sugar concentration of the neonates at arrival were choosen for quality control. The mortality of the newborn infants after admission was evaluated. The indications for transportation of severely ill infants are listed and the transport equipment is described.

Blood Gas Analysis↗

[Extrahepatic stenosis of the portal vein after infection or catheterization of the umbilical vein during the neonatal period (author's transl)].

147 children with high risk of developing a prehepatic portal vein obstruction were reexamined. The children had survived during their neonatal period:--Serious umbilical infection and sepsis (n=33)--Multiple exchange transfusion (n=55)--Long-term umbilical vein catheter treatment for at least 24 hrs (n=59). The reexamination at the age of 2--4 years revealed one case of total occlusion of the vena lienalis with partial obstruction of the vena portae in a child with former umbilical sepsis. Even though the etiologic relation of neonatal umbilical disorders and prehepatic portal obstruction is evident, the risk for the individual case seems to be low.

Catheterization↗

[Hyaline membrane disease: pulmonary changes and complications during ventilatory assistance in preterm infants (authors transl)].

The changing pattern of hyaline membrane disease and its iatrogenic complications during respiratory treatment are reviewed. The typical roentgenologic symptoms of pulmonary interstitial emphysema, pseudocyst, pneumomediastinum, pneumoperitoneum, pneumothorax, pneumopericardium, bronchopulmonary dysplasia and pulmonary heamorrhage are described and illustrated. Their relevance for clinical management is discussed.

Hemorrhage↗

Accessory diaphragm. Report of 6 cases and a review of the literature.

Six cases of accessory diaphragm, associated with respiratory symptoms are reported and of them two have so far been proved, by operation and autopsy, respectively. The described 15 cases in the medical literature are reviewed. The accessory diaphragm consists of a fibromuscular membrane separating the affected hemithorax into two cavities and in three cases a nerve supply has been reported. The diagnosis can be made by simple frontal and lateral roentgenograms of the chest. Typically they show a small lung with shift of the mediastinum to the affected side, an area of increased hazy density, lack of sharpness of the mediastinal structures and the cardiac border on the affected side and a characteristic strip of increased density paralleling the sternum in the lateral view. Roentgenologic differential diagnosis includes lobar atelectasis and pulmonary hypoplasia. There is a high incidence of associated pulmonary maldevelopment of the ipsilateral side and of vascular and cardiac malformations. Improper timing in the interaction of lung buds and septum transversum with the development of a double diaphragm possibly is responsible for this rare congenital anomaly. Usually it is encountered on the right side. Since pulmonary maldevelopment maintains repeated or chronic respiratory infections, recognition and operative therapy are essential.

Abnormalities, Multiple↗

Salicylate saturation index in neonatal jaundice.

30 serum samples from premature and newborn infants with non-haemolytic hyperbilirubinaemia were analyzed to prove the accuracy of determination of albumin binding capacity for bilirubin. The salicylate method of Odell was used to determine the saturation index of albumin indicated by a decrease in optical density through displaced bilirubin. Bilirubin is stoichometrically displaced from albumin by the addition of salicylate. The values of the sautration index correspond to free binding sites. Analysis of our data demonstrated that there is no direct correlation between the saturation index (SI) and total serum bilirubin/albumin concentration quotient. Methodical errors, problems in statistics and other theoretical concepts are discussed. The salicylate method is not suitable for accurate determination of albumin binding capacity for bilirubin.

Bilirubin↗

Portal hypertension in children following neonatal umbilical disorders.

10 children presented pre-hepatic portal vein obstruction during their first 6 years of life. 8 of them had massive esophageal varices, 1 died from acute esophageal hemorrhage. The perinatal history of these childre was studied: All of them had an abnormal birth history and all had been hospitalized during their neonatal period. In 5 of them an umbilical infection had been diagnosed, one had an injection of THAM and one other an exchange transfusion through an umbilical vein catheter. Pre-hepatic portal vein occlusion in children is presumed to be mainly an acquired disease resulting from neonatal umbilical disorders.

Child↗

[Mobile intensive-care-unit for transportation of premature and newborn babies at risc (author's transl)].

This is a technical report on a specially equipped ambulance for transportation of high-risk, seriously ill neonates. A mobile neonatal intensive-care-unit operating independently of the car utilized an Ohio-transport-incubator with 12V-DC portable power pak and collapsible stand, battery-operated ECG-monitor with optical and acoustical signal, a ECG-monitor with optical and acoustical signal, a battery-operated infusion pump, a Bird-respirator mark 8 with oxygen-blender, nebulizer and infant circuit with modification for PEEP as well as additional accessories. Ambulance-duty service is guaranteed by the German Red Cross (DRK) to facilitate transfer at any time, while skilled personal (physician, nurse) of the intensive care ward in on 24 hs call.

Electrocardiography↗

[Neonatal information system I: computer-adapted pregnancy and birth record (author's transl)].

A computerized documentation system for the main perinatal data of the newborn is presented. The information about pregnancy and birth are recorded on two optic mark reader forms. They can be used as a part of the conventional patient's history and as a transport document. The forms are recorded by simple pencil marking without further clerical effort for the staff. A direct data processing of the marked informations is possible with a computer. After two years' use of the new documentation system our information about the admitted newborns had markedly improved. An early regstration of pre- and pernatal risk factors is possible.

Electronic Data Processing↗

[Neonatal information system II: computer-adapted examination form for the newborn (author's transl)].

For the documentation of the neonatal status we use computer-adapted optic mark reader forms since 1972. All important symptoms and signs are scheduled on two sheets and are assigned by pencil marking. The forms can be read automatically and are suitable for data processing. A copy remains in the patients clinical file and can be used like a conventionally written status. The mark reader forms improved singificantly our knowledge about the newborn's status. The problems of introducing the new documentation into the hospital routine are reported.

Computers↗