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Biomedical subjects

L Y Tang

Publications and source records attributed to L Y Tang.

22 records · Page 2Linked to original sources
PubMed1989

[Studies on the variability of incubation period of vivax malaria following mosquito biting].

From September 1985 to May 1987, 30 people were experimentally infected by Anopheles sinensis infected with Plasmodium vivax isolated from northwestern part of Hunan Province. The findings displayed in graphs demonstrate that the incubation period was variably depended on the number of infective mosquitoes used in the experiment. The short incubation period of 15.8 +/- 1.9d was frequently observed in 6 persons bitten by 10 infected mosquitoes. However, when one mosquito was allowed to feed on each of 24 volunteers, the incubation period was either short (17.3 +/- 1.2d) or prolonged (284.7 +/- 37.7d) in the ratio of 1 to 1. Based on these data it is suggested that tertian malaria of long incubation period must exist everywhere in China. In addition, the rational classification of vivax malaria and the ratio between long and short incubation periods in nature are also discussed in detail.

Animals↗
PubMed1989

[Experimental studies on the incubation period and relapse patterns in vivax malaria in west Hunan].

The paper reports on some biological characteristics of Plasmodium vivax isolated from Cili County of Hunan Province. 27 volunteers inoculated with sporozoites were observed for 1.5 to 2 years. Treatment with chloroquine 1.5g base for 3 days was initiated on the first day of the primary attack and of each relapse. The data indicate that the first latent period in 13 cases developing malaria after short incubation period is very long, being 243.4 (191-297) days; however it is always short, being 55.3 (51-80) days in 14 patients with long incubation period. Definite relationship existing between incubation period and relapse patterns in vivax malaria is thus demonstrated.

Animals↗
PubMed1988

[Growth capability of epithelial cell line of human poorly differentiated nasopharyngeal carcinoma and its response to Chinese medicinal herbs and marine drugs].

By 3H-TdR incorporation, dye exclusion and cell colony-forming tests, the capability of short-term in vitro growth of the epithelial cell line of human poorly differentiated nasopharyngeal carcinoma (CNE-2Z) was assayed. At the same time, its response to 54 kinds of Chinese medicinal herbs and marine drugs was studied. The results showed that the 3H-TdR incorporation rate of cells was 1.8 +/- 0.02%, reproduction rate was 60.9 +/- 13.0% and colony-forming rate, 40.8 +/- 3.5%. As to the ratios of the three cell growth indexes and response to medicines, the Chinese medicinal herbs and marine drugs causing the reduction of colony-forming and cell survival ratios were predominant (64.8% and 40.7%). The results indicate that the majority of drugs possess the cytotoxic and inhibitory effect on cell reproduction to different degrees. The composite cell response to every kind of drug could be divided into 6 types: descending, ascending, peaked, valley-like, depressed and stable. The depressing type drugs might inhibit or arrest the cell growth of nasopharyngeal carcinoma and are worthy of further study.

Cell Division↗