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Biomedical subjects

L Yanko

Publications and source records attributed to L Yanko.

At least 37 records · Page 2Linked to original sources

Diabetic retinopathy in visual deprivation. A case report.

A case of asymmetric retinal involvement in a diabetic patient who has long been exposed to visual deprivation on one eye is described. The question implied by this condition is if a relationship could exist between the distinct exposure of each eye to different visual excitations, and the outcome of the different retinal diabetic involvement. The possibility that the retina in a resting state might be less prone to develop diabetic retinopathy than usual, and a possible functional hypothesis on the pathogenesis of this diabetic complication, are questioned.

Diabetic Retinopathy↗

Teratoid intraocular medulloepithelioma.

The right eye of a 1-year-old black infant with a painful blind eye was studied histologically. It contained a tumor at an advanced stage of growth. The tumor consisted of moderately large, round, and elongated undifferentiated cells and anaplastic cells with mitotic figures combined with multilayered, poorly differentiated epithelial cells that resembled the medullary epithelium of embryonic retina. Strap cells with cross striation typical of striated muscle were also present, together with islands of hyaline cartilage and areas of calcification.

Ciliary Body↗

Post partum renal failure due to progressive systemic sclerosis treated with chronic hemodialysis.

An unusual case of progressive systemic sclerosis with rapidly progressing renal failure after a successful delivery is described. The presenting syndrome was malignant hypertension. The blood pressure was refractory to the various therapeutic measures which were instituted, including hemodialysis. The patient, therefore, underwent bilateral nephrectomy, following which the blood pressure returned to normal, and she survived on hemodialysis for 17 months. To the best of our knowledge, the patient presented herein is the only reported case of this kind of fetal and maternal salvage.

Adult↗

Retinal vein occlusion.

A brief description is given of the main clinical, histological and epidemiological circumstances of retinal vein occlusion. In an assessment of the pathogeneis of the condition, primacy is given to the role of arteriolar flow insufficiency and stress is laid on the long-standing capillaropathy which precedes the heamorrhagic phase of the disease. Basic therapeutic considerations are mentioned but stress is laid on the diagnosis of the pre-occlusive stage and on measures of a preventive nature that may be taken. Retinal vein occlusion and haemorrhagic cerebral infarct are compared with regard to their pathogenesis and the advantages are discussed of a common ophthalmoscopic study of retinal vein occlusion with neurologists interested in cerebral vascular disease leading to an interchange of therapeutic experience in both conditions. Finally, there are detailed the studies in retinal vein occlusion being conducted by the Jerusalem Institute for the Prevention of Blindness. These are studies of incidence, natural history and of pathogenesis as observed in the experimental disease produced in rhesus monkey.

Cerebral Hemorrhage↗

Muscle capillaries and retinopathy among Israeli diabetics. With special reference to measurement techniques, relationship to age and the pericyte.

Our investigation of the capillaries of 64 Israeli diabetics confirm the fact that retinopathy is consistently associated with thickening of the basal lamina of peripheral muscle capillaries but the converse is not so. The change in pericapillary structure may affect the capillary function. The primary cell involved, either causally or as a consequence of the lexion, is the pericyte.

Age Factors↗

Gold tracer studies of muscle regeneration.

Rabbits were injected with soluble gold, and cold injury was inflicted upon their extraocular muscles. Following the typical freeze-thaw damage in which the myofiber basement membrane is preserved, a polymorphonuclear granulocyte exudation occurred. At this stage only a few interstitial cells with long processes contained gold. At one and two days abundant mononuclear cells with gold were observed at the site of injury. In subsequent stages of muscle regeneration the amount of tracer decreased but myoblasts, and even fully formed myotubes, often contained detectable gold. Some data on "in vivo" gold salt kinetics and the specificity of gold localization were utilised in the study of the relation between mononuclear interstitial cells and myoblasts.

Animals↗