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Biomedical subjects

L Yen

Publications and source records attributed to L Yen.

26 records · Page 2Linked to original sources
PubMed1984

Chromatographic resolution of the rod pigment from the four cone pigments of the chicken retina.

Chicken rod and cone pigments are chromatographically resolved using a combination of stepwise elution from a concanavalin A affinity column and a secondary ion exchange purification. The rod pigment rhodopsin and the cone pigment iodopsin are purified to homogeneity. There is a partial separation of three other cone pigments: chicken green, chicken blue, and chicken violet, making clear that this is at least a tetrachromatic cone system.

Animals↗
PubMed1980

Identification of mosquito blood meals by cellulose acetate and starch gel electrophoresis.

Cellulose acetate (CAE) and starch gel electrophoresis (SGE) were examined for their ability to identify species hemoglobins in mosquito blood meals. Blood meals analyzed serologically by the precipitin (PT) and passive hemagglutination inhibition (PHI) techniques served as standards for comparison. CAE, could not differentiate blood meals from divergent vertebrate hosts (man, rabbits, and mice) solely on the basis of the migratory properties of their respective hemoglobins. However, all could be differentiated when the migratory properties of both their hemoglobins and serum albumins were considered. CAE, like PT, was consistently able to identify blood meals for 18--24 hr post-ingestion. In contrast, PHI was able to identify blood meals for up to 48 hr post-feeding. SGE lacked the sensitivity of CAE, PHI and PT. SGE could only differentiate blood meals for 5--7 hr after ingestion. These results indicate that CAE has potential as a rapid technique for determining the origin of blood meals ingested by arthropod disease vectors.

Aedes↗
PubMedDate not supplied

Changes in health risks among the participants in the United Auto Workers--General Motors LifeSteps Health Promotion Program.

PURPOSE: To examine health risk changes among participants of a multicomponent worksite health promotion program. DESIGN: A study using health risk changes among health risk appraisal (HRA) participants linked to program participation records. Baseline risk and participation in multiple programs were examined in relation to risk change in multivariate models. SETTING: Worksite health promotion programming sponsored by the United Auto Workers (UAW) and General Motors (GM). SUBJECTS: Active employees (12,984) who voluntarily participated in an HRA in each of two program years. INTERVENTION: The nationwide program was a mailed HRA and a 1-800 nurse line. A pilot program (implemented in two cities) added screening, wellness programs, a materials resource, and, for high risk participants, health coaching and vouchers for medical office visits. MEASURES: Using 13 selected health risk factors from the HRA, changes in overall health risks were measured as program outcomes in three ways: one-directional, net, and risk status change. RESULTS: A greater decrease in the number of health risks was observed with increased program participation. The decrease was significantly related to the number of baseline risk factors and eligibility for high risk programs. Associated with program participation, the number of people at low risk status increased from 70.1% to 71.3% at year 2 among nationwide participants and from 52.4% to 58.9% among pilot participants. CONCLUSIONS: Participation was associated with a significant impact on health risk. Baseline risk of participants and eligibility for high risk programs were necessary factors to control when measuring program effects on health risk changes.

Health Promotion↗