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Biomedical subjects

L da Silva

Publications and source records attributed to L da Silva.

8 recordsLinked to original sources

[Rice and bean diets increase hepatic and plasmatic activity of gammaglutamyltranspeptidase in young rats].

The effect of feeding rice and bean diets in both hepatic and plasmatic activity of gamma-glutamyltranspeptidase-(GGT-EC 2.3.2.2) activity was evaluated in growing-rats (Experiment A) and mature rats (Experiment B). During 28 days, the animals were fed with isocaloric-diets composed by tree levels of rice, bean or rice-and-bean protein. Similarly with the aproteic group, a significant increase on both the hepatic and plasmatic GGT activity were showed with the lowest levels of protein, when compared with 25% casein control group. This rise was more effective in growing-rats fed on legume-based diets (as bean or rice-and-bean diets), making evident a differential effect of age and an exacerbated effect of the protein restriction with the lowest sulfur amino acids disposal. These alterations suggest a metabolic adaptation of GGT to both the inadequate protein and sulfur-amino acid levels, thus supporting the hypothesis that the Glutathione levels may be reduced by these legume-based diets.

Analysis of Variance↗

Comparison of the fracture resistances of pulpless teeth restored with a cast post and core or carbon-fiber post with a composite core.

STATEMENT OF PROBLEM: The survival of pulpless teeth restored with a post and core system is a controversial issue. PURPOSE: This study compared the fracture resistance of 2 types of restorations: teeth restored with prefabricated carbon-fiber posts and composite cores to cast dowel-core restored teeth. MATERIAL AND METHODS: A total of 44 recently extracted sound premolars were randomly distributed into 2 equal groups: group I, restored with prefabricated carbon-fiber post and a composite core; and group II, with custom-cast type III gold alloy post and cores. The size and shape of the posts were identical in the 2 groups. All teeth were fully covered with a nonprecious cast crown. Fracture resistance was measured by applying a point force at 45 degrees to the long angle of the tooth. RESULTS: Mean fracture threshold was 103.7 +/- 53.1 kg for group I versus 202.7 +/- 125.0 kg for group II (differences significant with P = .003). In group II, however, fracture nearly always affected the tooth itself, whereas in group I, the post-core nearly always failed first. CONCLUSIONS: Significantly higher fracture thresholds were recorded for the cast post and core group. Teeth restored with cast posts typically showed fracture of the tooth, although at loads rarely occurring clinically.

Adolescent↗

A follow-up study of severe puerperal psychiatric illness.

The outcome in clinical and social terms of a psychiatric illness arising within 1 year of confinement or termination of pregnancy and requiring on-going care was studied after a period of 1-6 years in 47 women. The outcome was related to the earlier features of the illness and to personal and historical features. Social impairment and continuing psychopathology occurred in many cases. The only factor which significantly related to poor outcome was an initial diagnosis of schizophrenia.

Abortion, Induced↗