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Biomedical subjects

L von Ferber

Publications and source records attributed to L von Ferber.

8 recordsLinked to original sources

[Estimation of the incidence of diabetes in the Federal Republic of Germany based on insurance data. A secondary data analysis of a representative random sample of locally insured persons in the city of Dortmund].

All records relating to medical prescriptions and services relating to diabetes for a representative sample (n = 6478) of inhabitants of Dortmund in 1988, who were members of the Local Health Insurance in Dortmund, were analysed. 264 patients (4.08%) were receiving antidiabetic drugs during that year, 198 (3.06%) oral ones, 42 (0.65%) insulin and 24 (0.37%) both. 12.41% of all those insured over the age of 60 were on antidiabetic drugs, more women than men (5.08 vs 2.94%; P less than 0.001). The most frequently used oral antidiabetics were sulphonylurea ones (95.1%), while the proportion of biguanides was only 4.4%. On the basis of established diagnosis, regular blood sugar and HbA1 tests, as well as optic fundi examination, a further 104 persons (1.60%) are assumed to have diabetes but not treated by drugs. This sample indicates an overall prevalence of diabetes of 5.68% among the population. Relating it to the age and sex pattern of the population of the Federal Republic of Germany this corresponds to a prevalence of diagnosed diabetes of 4.82%. Thus there are probably a little less than 4 million diabetic citizens of the Federal Republic of Germany.

Age Factors

Drug utilization research in primary health care as exemplified by physicians' quality assessment groups.

Drugs in primary health care are often prescribed for nonrational reasons. Drug utilization research investigates the prescription of drugs with an eye to medical, social and economic causes and consequences of the prescribed drug's utilization. The results of this research show distinct differences in drug utilization in different age groups and between men and women. Indication and dosage appear irrational from a textbook point of view. This indicates nonpharmacological causes of drug utilization. To advice successfully changes for the better quality assessment groups of primary health care physicians get information about their established behavior by analysis of their prescriptions. The discussion and the comparisons in the group allow them to recognize their irrational prescribing and the social, psychological and economic reasons behind it. Guidelines for treatment are worked out which take into account the primary health care physician's situation. After a year with 6 meetings of the quality assessment groups the education process is evaluated by another drug utilization analysis on the basis of the physicians prescription. The evaluation shows a remarkable improvement of quality and cost effectiveness of the drug therapy of the participating physicians.

Cost-Benefit Analysis

[General practitioners and internists prescribe psychopharmaceutic drugs].

An epidemiological study using data from a local German health insurance fund on the psychotropic drug prescription of physicians and the drug utilisation of their patients is presented. Taking a sample of 280 out-patients, descriptive methods are presented (defined daily dose (DDD), prescribed daily dose (PDD), active-agent-oriented classification of drugs, therapy-oriented classification of diagnoses). The following questions are answered by this study: Which patients with which indication received which dosage of which psychotropic drug for how long from which physicians? The patient-based structure of the data, taking into account the prescriptions of all physicians allows the course of therapies and the study of overall psychotropic medication. Prevalences estimates concerning the patients are also possible. Our results are compared with those of similar pharmaco-epidemiological studies; the difference in prevalence estimates, as well as advantages and possible disadvantages arising from the use of such secondary data base, are discussed.

Aged

[What is social pharmacology, what are its goals?].

Sociopharmacology is based on interdisciplinary research involving pharmacology, epidemiology, social medicine and sociology. It aims at finding out the social determinants of drug intake. How this goal is approached stepwise is shown in the case of the benzodiazepine group of active substances.

Adolescent