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Biomedical subjects

Lütfullah Beşiroğlu

Publications and source records attributed to Lütfullah Beşiroğlu.

7 recordsLinked to original sources
PubMed2006

[The correlates of healthcare seeking behavior in obsessive-compulsive disorder: a multidimensional approach].

Obsessive-compulsive disorder (OCD) is a chronic, distressing, and disabling illness that influences the family, academic, occupational, and social functioning of patients. One of the 10 leading causes of disability worldwide is OCD; however, despite the considerable distress and disability associated with the disorder and the availability of treatment options, many OCD sufferers usually are not inclined to seek healthcare. The factors that may be central to healthcare seek behavior in OCD has scarcely been described in the literature. It has been thought that the best predictor of healthcare seeking is severity of illness; however, individuals with OCD may have various barriers to seeking healthcare. Although non-disease and disease-related factors that may influence health care seeking are related in complex ways through reciprocal influences and feedback, each factor might be an independent predictor of use of healthcare services. This review aims to discuss the impact of the disease and general factors that impact healthcare seeking behavior in OCD. In this way, new information might be provided for the identification of targets to enhance the use of mental health services among OCD sufferers in the community.

Humans↗
PubMed2005

[The assessment of obsessive-compulsive symptoms: the reliability and validity of the Padua inventory in a Turkish population].

OBJECTIVE: We examined the reliability and validity of the 60-and 41-item versions of the Padua Inventory (PI and PI-R) which were developed to assess the frequency and severity of obsessive-compulsive symptoms, in a Turkish population. METHOD: The sample consisted of 43 OCD patients, 30 non-OCD patients with other anxiety disorders, 30 nonobsessional depressed patients, 76 healthy adults, and 181 undergraduate students. We investigated internal consistency, test-retest reliability, and factor structure, concurrent and discriminant validity. RESULTS: Psychometric analyses showed that both the original PI and PI-R had a high internal consistency and test-retest reliability. While principal factor analysis of the 41 items revealed six factors that are consistent with the PI-R, the factor structure of the original scale was not confirmed. All the subcales and total scores for both instruments were significantly correlated with the Yale-Brown scores except for the impulses subscale. There were significant differences between OCD patients and nonclinical samples in all total and subscale scores for both instruments. OCD patients scored significantly higher on the total, contamination/washing and checking subscales for both instruments than nonobsessional anxious, and depressed patients. While OCD patients scored significantly higher on the PI-R rumination scale than nonobsessional anxious patients, their PI impaired control subscale score was not different from that of the other clinical groups. CONCLUSIONS: The Turkish version of the PI has appropriate reliability and validity for assessing the frequency and severity of obsessive-compulsive symptoms.

Adolescent↗
PubMed2004

[The reliability and validity of the White Bear Suppression Inventory].

OBJECTIVE: The White Bear Suppression Inventory (WBSI) is a self-report questionnaire measuring tendency to suppress unwanted intrusive thoughts. The aim of this study was to examine the reliability and validity of the WBSI in a Turkish sample. METHOD: Thirty patients who were diagnosed with obsessive-compulsive disorder (OCD) according to DSM-IV criteria and 47 healthy subjects were included in the study. Internal consistency and homogeneity were tested by Cronbach a and Pearson correlation analysis. Student's t test and Pearson correlation analysis were used for test-retest reliability. Validity was assessed by Student's t test in independent groups. RESULTS: Psychometric analyses showed that the WBSI had a high internal consistency (a=0.92). All of the items' scores were positively correlated with the total scores. The items of the WBSI discriminated the patients with OCD from the healthy subjects except for item 5. CONCLUSIONS: The Turkish version of the WBSI has appropriate reliability and validity for assessing suppression tendency of unwanted intrusive thoughts.

Adult↗
PubMedDate not supplied

Serum lipid levels, suicidality, and panic disorder.

Although the effects of serum total cholesterol and other lipids have been implicated as a predictor of suicidal behavior in major depression, the role of cholesterol level on suicide risk for panic disorder patients is not considered as a biological marker in the literature. In this study, we examined the relationship of suicidality with serum cholesterol concentration in panic disorder. The subjects of the study were 10 suicidal panic disorder patients, 19 nonsuicidal panic disorder patients, and 15 normal control subjects. The suicidal patients with panic disorder had lower serum total cholesterol and low-density lipoprotein (LDL) levels than normal control subjects. These findings suggest that there may be an association between suicidality and low serum cholesterol levels in panic disorder. We also discuss the possible role of serotonin in the brain in the relationship of suicidal behavior or ideation with low cholesterol concentration in panic disorder.

Adolescent↗
PubMedDate not supplied

The predictors of health care seeking behavior in obsessive-compulsive disorder.

A majority of individuals with obsessive-compulsive disorder (OCD) do not seek health care. To better understand why not, health care-seekers (HCS) with OCD (n = 25) were compared with non-health care-seekers (NHCS) with OCD (n = 23) regarding their sociodemographic variables, symptom severity, types of obsessions and compulsions, insight degree, comorbid diagnosis, and quality-of-life (QOL) level. There was no significant difference for sociodemographic characteristics between the groups. NHCS scored significantly lower on a measure of illness severity than HCS. The NHCS group had significantly poorer insight degree than the HCS group. Aggressive and religious obsessions were significantly less identified in the NHCS group compared to the HCS group. NHCS were significantly less likely to have comorbid diagnosis than HCS. The NHCS group reported significantly higher levels of QOL in psychological health and level of independence domains [corrected]. To identify the predictors of health care seeking behavior, probable variables were entered in a logistic regression model. Insight degree and level of independence emerged as the predictors of health care seeking. Our results suggest that health care seeking behavior in OCD is associated with the individuals' ability to recognize their symptoms as a disorder and subjective interpretation regarding the impact of OCD on their level of independence. Results of the present study extend findings of two recent studies that have investigated factors related to health care seeking in OCD.

Adult↗