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Larry M. Baddour

Publications and source records attributed to Larry M. Baddour.

4 recordsLinked to original sources
PubMed2004

Intra-arterial Device Infections.

As an increasing number and variety of prosthetic devices are used in cardiovascular medicine, novel infectious complications have been described. Infection of intra-arterial devices, including arterial closure devices, prosthetic carotid patches, coronary artery stents and endovascular stents, and stent-grafts, is now being reported. Prosthetic vascular graft infection is an older, more common, and better-characterized entity, but recent developments in the surgical management of these infections have prompted a re-examination of the syndrome. Staphylococcal species account for most intra-arterial device infections, and often, morbidity and mortality rates are high. An update on intra-arterial device infections is warranted.

Journal Article↗
PubMed2002

Nonvalvular Intravascular Device-related Infections.

Nonvalvular intravascular devices are in widespread use in developed countries and are now more commonly employed than are prosthetic cardiac valves. Although the variety of devices that are included in the category of "nonvalvular" represent a heterogenous collection, there is commonality among several of the devices. This includes their requirement to sustain life and the need for removal for cure if they become infected, which is often due to multidrug-resistant microorganisms. Thus, infection of these devices often presents difficult treatment scenarios. This update will address the pathogenesis and immunobiology of nonvalvular intravascular device-related infections and the epidemiology and treatment of infections of several of these devices that include pacemakers, implantable cardioverter defibrillators, intravascular catheters, vascular grafts and stents, and left ventricular assist devices.

Journal Article↗
PubMed2001

Recent Considerations in Recurrent Cellulitis.

Cellulitis is a frequently diagnosed syndrome that causes considerable morbidity. For a subset of patients, recurrent bouts of infection impact their quality of life. Most cases are due to beta-hemolytic streptococci or Staphylococcus aureus. Inclusion of interdigital space (toe web) or mucosal (anal) swab cultures may increase the ability to define pathogens among patients with lower extremity cellulitis. The pathogenesis of cellulitis is complex, and more work is needed so that novel therapies and vaccines can be developed to improve treatment and prevention of this disorder.

Journal Article↗