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Biomedical subjects

Leif Aanderud

Publications and source records attributed to Leif Aanderud.

4 recordsLinked to original sources

Hypermetropia-succeeded myopia after hyperbaric oxygen therapy.

A 58-year-old man presented with a change in vision during hyperbaric oxygen (HBO) therapy. Subsequent follow-up visits showed a hypermetropic shift, which succeeded the myopic shift after each of two series of HBO treatments. The maximal refractive amplitude was 3.00 D (range -1.37 D to +1.62 D) in the right eye and 2.75 D (range -1.25 D to + 1.50 D) in the left eye. Refraction stabilized after 1.5 years at +0.62 D and +0.50 D to pretreatment values in the right and left eye, respectively. The findings are discussed with regard to possible changes in the structure of the lens.

Follow-Up Studies↗

Time and temperature effects on body fluid loss during dives with the open hot-water suit.

BACKGROUND: Bodyweight (BW) losses up to 5 kg have been observed during diving with the open hot-water suit (HWS). The objective of these dives was to study the hormonal, hematological, and renal effects of dehydration during shallow HWS diving. METHODS: In series 1, four divers dove for 3.5 h each day for 7 d. In series 2, 12 divers dove to 6-8 msw for 1, 2, and 4 h. Blood and urine samples, BW measurements, oral temperature, and thermal stress indices were collected. RESULTS: Average deltaBW (+/- SD) for the 28 dives in series 1 was 1.5 +/- 0.8 kg, and the largest BW reductions were 3.2 and 3.0 kg, corresponding to 3.7 and 4.7% of BW. Changes in thermal stress, hemoglobin, hematocrit, aldosterone, and electrolyte excretion correlated with BW reduction. In series 2, average BW reductions were 0.46 +/- 0.27, 0.96 +/- 0.38, and 1.55 +/- 0.59 kg during 1-, 2-, and 4-h dives. BW reduction correlated significantly with thermal stress (p < 0.01). Aldosterone increased after 1 and 2 h and plasma renin activity was unchanged. Atrial natriuretic peptide increased in all dives (p < 0.01) and arginine vasopressin increased in the 4-h dives (p < 0.05). The 7.2% decrease in plasma volume, the increases in hemoglobin, hematocrit and serum proteins, and an unchanged plasma osmolality indicate an isotonic dehydration after the 4-h dives. CONCLUSIONS: BW loss during HWS diving is mainly caused by sweating. Dives of 4 h produce an isotonic dehydration and a break for fluid intake is, therefore, recommended.

Adult↗

Ocular refractive changes in patients receiving hyperbaric oxygen administered by oronasal mask or hood.

PURPOSE: The aim of this study was to quantify ocular refractive changes after a standard hyperbaric oxygen (HBO) treatment protocol and to characterize the time period of recovery. PATIENTS AND METHODS: Hyperbaric oxygen therapy was given for 90 min daily at a pressure of 240 kPa for 21 days. Oxygen was administered to 20 patients using an oronasal mask and to 12 patients using a hood. Follow-up examinations were carried out 2-4 days after treatment, and thereafter regularly for up to 10 weeks in both groups. Refraction was assessed automatically and by the monocular subjective refraction method. A subgroup of nine of the 20 patients to whom oxygen was administered by an oronasal mask underwent a separate eye examination, which included crystalline lens opacity measurements and LOCS III gradings. RESULTS: In the patients given oxygen by mask, there was a significant myopic shift in the mean spherical equivalent, which was largest 2-4 days after treatment. The shift was - 0.55 +/- 0.40 D in the right eye and - 0.53 +/- 0.42 D in the left eye. In the patients given oxygen by hood, the largest shift was observed after 12-16 days, and was - 1.06 +/- 0.52 D in the right eye and - 1.10 +/- 0.57 D in the left eye. The refractive changes returned to baseline 6 weeks and 10 weeks after HBO treatment, respectively. No significant changes in crystalline lens transparency were revealed. CONCLUSIONS: The myopic shift after HBO therapy recovers within 10 weeks and may be more pronounced when patients are given oxygen using a hood compared with using an oronasal mask.

Cystitis↗

[Neurologic decompression sickness in sports divers].

BACKGROUND: Sports diving is a popular recreational activity. Sports divers presenting with acute decompression sickness may exhibit residual neurologic and neuropsychological symptoms during follow-up, in spite of appropriate treatment. MATERIAL AND METHODS: A retrospective review of medical records was carried out for sports divers admitted to the department of neurology at Haukeland University Hospital during 1997. RESULTS: 11 out of 20 divers experienced residual neurological symptoms after treatment. Five responded poorly to treatment, with 50% or more residual clinical score. These patients tended to be older, had performed deeper dives, and more repetitive diving. Seven divers had increased slow wave activity in EEG on initial recording, in two the EEG changes persisted after treatment. INTERPRETATION: In this small series of sports divers with decompression sickness and arterial gas embolism, most neurologic symptoms responded to hyperbaric treatment. However, more than one half of the divers had residual neurological symptoms on discharge. Sensory loss and asymmetrical reflexes were the most common residual findings.

Adult↗