PubMed Health⌕ Search

Biomedical subjects

Leonardo Emberti Gialloreti

Publications and source records attributed to Leonardo Emberti Gialloreti.

4 recordsLinked to original sources

Analysis of the cost-effectiveness of varicella vaccine programmes based on an observational survey in the Latium region of Italy.

Varicella is the most widespread childhood disease in Italy. However, as in many parts of the world, the country does not yet have a unified approach to the management of the disease. A cost-effectiveness analysis of varicella vaccination strategies, using the Latium region in Italy as a case study, was undertaken. Mass vaccination is only recommended if the immunization programme can achieve coverage of over 85% in a short time. However, experience in Italy with non-compulsory vaccinations has shown this is difficult to achieve. Consequently, eradication of the disease is not seen as an attainable short-term goal. For mass varicella vaccination to be successful, it must be run at a national as well as regional level in combination with education programmes, and a reliable surveillance system. The interaction between varicella and herpes zoster must also be taken into account when considering vaccination strategies, as zoster vaccination strategies may have an impact on varicella coverage.

Acyclovir↗

Auditory sensory processing in autism: a magnetoencephalographic study.

BACKGROUND: Patients with autism show clinical features suggestive of abnormal processing of auditory and other sensory information. We hypothesized that low-functioning autistic subjects present abnormalities in discriminating simple auditory stimuli at sensory system preconscious stages of cortical processing. METHODS: To verify our hypothesis, we used magnetoencephalographic measurements of mismatch field (MMF), which reflects the detection of a change in the physical characteristics of a repetitive sound. Fourteen patients (aged 8-32 years) who met DSM-IV diagnostic criteria for autistic disorder participated in an auditory oddball experiment. Ten healthy participants matched for age and gender acted as control subjects. RESULTS: Significant differences in cerebral responses between patients and control subjects were recorded. Whereas control subjects showed a clearly identifiable MMF, with distinct generators in the M100 brain wave with regard to latency, position, and strength, no identifiable MMF was present in the autistic group. CONCLUSIONS: Our findings suggest that low-functioning autistic subjects present a dysfunction at preconscious stages of cortical auditory discrimination, playing a role in the abnormal processing of auditory sensory afferences. The attention independence of the MMF allows for exclusion of an effect related to impaired attention or task-related responses.

Acoustic Stimulation↗

[DREAM project early results (drug resources enhancement against AIDS in Mozambique)].

This study is aimed at assessing the outcomes of home care treatment for people living with AIDS in Mozambique. The authors have analysed data from 62 adult patients undergoing a Home Care Program carried out by the Sant'Egidio Community, Italy and the Sue Ryder Care in Matola, Mozambique. The above-mentioned program complies with the WHO guidelines and provides for free antiretroviral therapies and laboratory exams. After hardly two-year treatment, the mortality rate of the sub-sample examined dropped by nearly 80%. Both compliance and adverse reactions have shown to be similar to the reported levels in developed countries. This program is unprecedented in Mozambique and has proved extremely effective for the affected population.

English Abstract↗