Li Hua Yu | PubMed Health

PubMed2005

High-gain harmonic generation free-electron laser with variable wavelength.

The external seed of the high-gain harmonic generation (HGHG) free-electron laser (FEL) determines the wavelength of the output radiation. Therefore, the tunability of such a laser depends upon the tunability of the seed. In this paper, we present and discuss an alternative scheme for the tunable HGHG FEL wherein the seed's wavelength is fixed and the variations in the wavelength of radiation are achieved by tuning the accelerator. As an illustration, we apply our proposed scheme to the deep ultraviolet free electron laser (DUV FEL) at Brookhaven National Laboratory demonstrating the ability to attain about a +/-10% variation in the wavelength's tuning range.

Journal Article↗

PubMed2002

Induction of mammalian cell death by a plant Bax inhibitor.

Arabidopsis thaliana AtBI-1 is an orthologue of mammalian Bax inhibitor-1 capable of suppressing Bax-induced cell death in yeast as well as mammalian cells. Here we investigated whether or not AtBI-1 suppresses Bax-induced cell death using human fibrosarcoma HT1080 cells. Surprisingly, AtBI-1 did not block Bax-induced cell death, but it triggered apoptotic cell death in mammalian cells. The proapoptotic effect of AtBI-1 was blocked by the X-linked caspase inhibitor XIAP, suggesting that the cell death caused by AtBI-1 is similar to that caused by Bax.

Apoptosis↗