PubMed Health⌕ Search

Biomedical subjects

Li-sheng Yu

Publications and source records attributed to Li-sheng Yu.

6 recordsLinked to original sources
PubMed2006

[Immunohistochemical discrimination of aggressivity between the cholesteatoma from different positions].

OBJECTIVE: To investigate whether the cholesteatoma from different positions have different biological characteristics. METHODS: The expression of the Ki-67 and collagen IV in 19 specimens of cholesteatoma were stained immunohistochemically using the SP method, according to the origin of the specimens, include 7 cases from the epitympanum, 8 cases from tympanic sinus and 4 cases from the out acoustic canal. According to the severity of the inflammation in the perimatrix, the inflammation group included 7 cases, the non-inflammation group included 8 cases. RESULTS: The average count was the same between the cholesteatoma from epitympanum and tympanic sinus. And the count of the cholesteatoma in the middle ear was also the same to the cholesteatoma from the out acoustic canal. But even from the same sample, the cholesteatoma from the positions with severe inflammation in the perimatrix count much higher, and the difference was statistically significant. Collagen IV had been found to localized in the basic membrane. In some specimens the staining of the collagen IV was not continuous. CONCLUSIONS: The results suggested that it was the severity of inflammation in the perimatrix influenced the differences, but not the origins of the cholesteatoma.

Adolescent↗
PubMed2004

[Operative therapy of the adhesive otitis media].

OBJECTIVE: To study the operative indications and treatment for adhesive otitis media (AOM). METHODS: Sixty-nine cases of AOM were undergone tympanoplasty between 1995 to 2000. Preoperative average air-bone gap(A-B gap) were (43.7 +/- 3.9) dB. Forty-one cases could be postoperative followed up for more than one year. Preoperative average A-B gap of this group were (43.8 +/- 4.2) dB. The adhesive ear drum and the other processes in middle ear were inserted and reconstructed with cartilage. RESULTS: The postoperative average A-B gap after one month(69 cases) and one year(41 cases) were (23.7 +/- 8.6) dB and (27.9 +/- 10.7) dB. In the long-time follow-up group, the A-B gap of 18 cases (43.9%) were less than 20 dB. Twenty-four cases (58.5%) become a nearly normal tympanum. CONCLUSION: The AOM can treatment with tympanoplasty. But the indication must be carefully selected. The cartilage was a good material for reconstruction of the ear drum to treatment the AOM. The influence factor were analyzed.

Adult↗
PubMed2004

[Cochlear reimplantation].

OBJECTIVE: To analyze retrospectively the outcome of 6 cases of cochlear reimplantation to summarize its experience. METHODS: The operation method of cochlear reimplantation was similar to routine cochlear implantation. A "H" incision for the muscle-periosteum was used to shorten the operation time. RESULTS: Of all the cases, the electrodes are successfully and totally inserted into the cochlea. The causes for revision are different. The electrode was found to be not in the proper situ of the cochlea after the first operation in one patient. The out part was ruptured because of trauma in another patient. The causes of the other four patients were unknown. CONCLUSIONS: The incision should not be too small. The control electrode should be put beneath the periosteum. The site used to fix up the out part need be burnished. Unabsorbable suture should do not be used. It is important to insert the new electrode quickly after drawing the old one out. The time to accommodate the new electrode often needs 3-4 weeks.

Adolescent↗
PubMed2003

[Comparison of tolerance to sequential continuous positive airway pressure therapy between patients after classical and after modified uvulopalatopharyngoplasty].

OBJECTIVE: To investigate the effect of uvulopalatopharyngoplasty (UPPP) on postoperation continuous positive airway pressure (CPAP) treatment in patients with obstructive sleep apnea hypopnea syndrome (OSAHS). METHODS: 66 OSAHS patients underwent UPPP were recruited and all were followed up for more than 12 months. Among them 24 patients were treated with classical UPPP, 42 had modified UPPP treatment. The efficacy of surgery was compared between the two groups. The post-operation tolerance to CPAP pressure was tested during sleep CPAP titration in 24 classical UPPP patients and in 15 modified UPPP patients. RESULTS: The validity ratio is 58.3% and 61.9% 12 months after operation. There was no significant difference between classical UPPP and modified UPPP in regard to surgery efficacy, and most of them need further CPAP therapy. During CPAP treatment, compared with untreated OSAHS patients, the highest CPAP pressure classical UPPP group could tolerant decreased significantly, however, classical UPPP group did not. 16.7% of classical UPPP patients had severe mouth air leak before optimal CPAP pressure was titrated, but none of the 15 post modified UPPP failed to sequential CPAP therapy. CONCLUSION: The efficacy was similar between modified UPPP and classical UPPP treatment, post modified UPPP patients had better tolerance to sequential CPAP treatment. It may be better to treat OSAHS patients with modified UPPP instead of classical UPPP.

Adult↗