Biomedical subjects
Publications and source records attributed to Long Truong.
We discuss a new type of deformable mirror made from nanoengineered reflective layers deposited onto liquids. The surfaces are shaped by heating with a laser. The response times of the deformed surfaces are slow (> 1 s). Simplicity and low cost appear to be the main advantages of thermally deformable liquid mirrors.
An efficient method for the solid-phase synthesis of hydantoins and thiohydantoins tethered to ureas, starting from a resin-bound amino acid, is presented. Following reduction of the amide with borane-THF, a second amino acid was selectively coupled to the primary amine followed by treatment of the secondary amine by an isocyanate to generate the corresponding urea. Hydantoin and thiohydantoin formation was achieved through the use of carbonyldiimidazole and thiocarbonyldiimidazole, respectively. Cleavage from the solid support using hydrogen fluoride, followed by extraction and lyophilization, provided the desired urea-linked heterocyclic compounds in good yield and high purity.