PubMed Health⌕ Search

Biomedical subjects

Lorenzo Bison

Publications and source records attributed to Lorenzo Bison.

2 recordsLinked to original sources

[Multislice CT fluoroscopy: technical principles, clinical applications and dosimetry].

PURPOSE: The aim of this study is describing fluoroscopic techniques with multislice CT during interventional procedures. We emphasize the technical principles of the multislice CT fluoroscopy and the relative advantages in clinical application, in comparison to single slice fluoroCT and conventional CT guided procedures. Other topics are dosimetry and patient's and operator's radioprotection. MATERIALS AND METHODS: We describe our experience in 60 cases of interventional procedures performed with CT fluoroscopy array for the TOSHIBA AQUILION-MULTI TSX-101A scanner that allows a real-time 3 slices simultaneous representation of the target: middle target slice, superior and inferior slices. Thirty nine biopsies, 5 abscess drainage, 12 shoulder arthrocentesis previous to arthro-MR and 4 hepatic neoplasm ablations have been performed during the last 9 months. For each procedure questionnaires have been used to evaluate: target organs, scan parameters, fluoroscopy techniques (continuous or spot) and total time of fluoroCT. Basing on these data and on the measurements made on a body phantom we calculated patient's and operator's radiation dose rate. RESULTS AND DISCUSSION: The real-time simultaneous representation of the middle target slice and the adjacent superior and inferior slices has always allowed an immediate identification of the needle tip and direction. The use of a needle holder has been determined by the needle type, the fluoroscopy technique (continuous or spot), the type of interventional procedure and the target. In our experience freehand spot fluoroscopy approach was easier, faster and with less radiation dose rate. 24 seconds were the mean fluoroscopy time for all different CT fluoroscopy modalities and procedures. The mean absorbed equivalent dose rate to patient's skin was 5300 microSv/s while the dose to operator's body and hand was respectively 0.3 microSv/s and 30 microSv/s. CONCLUSIONS: Multislice CT fluoroscopy, specially if performed by spot technique, leads to an acceptable radiation dose rate to patient and operator, is user friendly and guides interventional procedures with rapidity.

Fluoroscopy↗

Abdominal recurrence of ovarian cancer: value of abdominal MR in patients with positive CA125 and negative CT.

PURPOSE: To evaluate the role of abdominal MR in the diagnosis of ovarian cancer recurrence in patients with increasing serum Ca-125 levels and negative abdomino-pelvic CT scan. MATERIALS AND METHODS: In a period of about 30 months, 22 patients in follow-up for ovarian carcinoma (stages II, III-IV) with increasing levels of Ca-125 and negative abdomino-pelvic CT scan were studied with abdomino-pelvic MR. All patients had a disease-free interval of at least 6 months after cytoreductive surgery and chemotherapy. MR examinations were performed with T1- and T2-weighted SE and FSE sequences in the axial and coronal planes, before and after Gadolinium administration. Tumour recurrence was confirmed at surgery, percutaneous biopsy and by monitoring progression or remission of the disease with clinical examination, Ca-125 serum levels and integrated imaging (CT and MR) during and after medical therapy. RESULTS: MR imaging demonstrated recurrence of the disease in 16 of the 22 patients, 3 of the remaining 6 patients were true negatives, whereas 3 patients were false negatives (in one case the CT and MR studies missed the peritoneal seeding found at surgery performed 1 month after the MR; in 2 cases both the CT and MR scans became positive for abdominal recurrence after 3 and 4 months respectively). The sensitivity and diagnostic accuracy of MRI were 84% (16/19) whereas specificity was 100% (3/3). The positive predictive value was 100% (16/16) whereas the negative predictive value was 50% (3/6). CONCLUSIONS: In a selected population of women with increasing serum Ca-125 levels and negative abdominal CT, MR imaging could supply earlier information about the presence and location of recurrences with a high impact on further decisions regarding the choice of therapeutic options (surgical or medical). The limited number of patients requires additional studies to confirm these resuts.

Abdominal Neoplasms↗