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Biomedical subjects

Lorenzo Franchi

Publications and source records attributed to Lorenzo Franchi.

32 records · Page 2Linked to original sources
PubMed2005

Class II malocclusion with maxillary protrusion from the deciduous through the mixed dentition: a longitudinal study.

The aim of this study was to analyze the skeletal characteristics of Class II malocclusion with maxillary protrusion in the deciduous dentition and to describe the growth features of this type of skeletal imbalance during the transition from the deciduous through the mixed dentition. A group of 17 subjects having skeletal Class II malocclusions in the deciduous dentition due to maxillary protrusion was compared with a control group of 30 untreated subjects with ideal occlusion at the same stage of development. Both groups were observed for the first time in the deciduous dentition (T(1)) and followed during the transition from the deciduous to the mixed dentition (T(2)). During this time no orthodontic treatment was provided. Lateral cephalograms were taken for all subjects at T(1) and T(2). A cephalometric analysis was performed based on a reference system that consisted of two perpendicular lines traced through stable basicranical structures. The results indicate that a Class II skeletal pattern due to a maxillary protrusion is established early in the deciduous dentition and remains unmodified in the transition to the mixed dentition. The maxilla appeared to be displaced forward in Class II subjects, whereas the mandibles of the Class I and Class II subjects did not show any significant differences at this stage of growth. In the passage from the deciduous through the mixed dentition, Class I and Class II subjects showed growth increments that were not significantly different from each other. Sucking habits appeared to be correlated with the skeletal maxillary protrusion.

Cephalometry↗
PubMed2004

Dentoskeletal effects induced by rapid molar distalization with the first class appliance.

The purpose of this study was to evaluate the treatment effects of the first class appliance (FCA; Leone, Firenze, Italy), a new intraoral device for unilateral or bilateral rapid molar distalizaton. A retrospective study was conducted to compare the predistalization and postdistalization cephalograms of 17 patients (10 male, 7 female) with Class II malocclusions treated with the FCA. Mean age at the start of treatment was 13 years 4 months. The FCA produced rapid molar distalization, and the bilateral Class II molar relationship was corrected in 2.4 months, on average. Maxillary molar distalization contributed to 70% of the space created anterior to the first molars; 30% of the space was due to reciprocal anchorage loss of the maxillary second premolars. The maxillary first molars showed a significant distalization of 4.0 mm, associated with a significant distal axial incline of 4.6 degrees and a significant extrusion of 1.2 mm. As for anchorage loss, the second premolars exhibited a significant mesial movement of 1.7 mm, associated with a significant mesial axial incline of 2.2 degrees and a nonsignificant extrusion of 1.0 mm. In the anterior region, a significant mesial movement of the maxillary incisor of 1.3 mm was associated with a significant incisor proclination (2.6 degrees ) and a significant increase in overjet (1.2 mm). No significant changes in either sagittal or vertical skeletal relationships were observed. The results suggest that the FCA is an efficient and reliable device for distalizing the maxillary permanent first molars.

Adolescent↗
PubMed2004

Cephalometric variables predicting the long-term success or failure of combined rapid maxillary expansion and facial mask therapy.

The aim of this study was to select a model of cephalometric variables to predict the results of early treatment of Class III malocclusion with rapid maxillary expansion and facemask therapy followed by comprehensive treatment with fixed appliances. Lateral cephalograms of 42 patients (20 boys, 22 girls) with Class III malocclusion were analyzed at the start of treatment (mean age 8 years 6 months +/- 2 years, at stage I in cervical vertebral maturation). All patients were reevaluated after a mean period of 6 years 6 months (at stage IV or V in cervical vertebral maturation) that included active treatment plus retention. At this time, the sample was divided into 2 groups according to occlusal criteria: a successful group (30 patients) and an unsuccessful group (12 patients). Discriminant analysis was applied to select pretreatment predictive variables of long-term treatment outcome. Stepwise variable selection of the cephalometric measurements at the first observation identified 3 predictive variables. Orthopedic treatment of Class III malocclusion might be unfavorable over the long term when a patient's pretreatment cephalometric records exhibit a long mandibular ramus (ie, increased posterior facial height), an acute cranial base angle, and a steep mandibular plane angle. On the basis of the equation generated by the multivariate statistical method, the outcome of interceptive orthopedic treatment for each new patient with Class III malocclusion can be predicted with a probability error of 16.7%.

Adolescent↗
PubMed2004

A cephalometric comparison of treatment with the Twin-block and stainless steel crown Herbst appliances followed by fixed appliance therapy.

This study compared the effects of 2 treatment protocols for correcting Class II disharmony. The first phase of treatment consisted of functional jaw orthopedics with either the Twin-block or the stainless-steel crown Herbst appliance; the second phase consisted of comprehensive fixed-appliance therapy in both protocols. Each of the 2 samples comprised 28 consecutively treated Class II patients. The mean age at the start of treatment was approximately 12 years, and the mean age at the end of the treatment was approximately 14.5 years in both groups. The duration of the treatment phase with the functional appliance was approximately 13 months, and the duration of fixed-appliance therapy was approximately 15 months in both groups. The sex distribution was identical in the 2 groups. Lateral cephalograms were analyzed at the start of treatment (T1) and at the end of the overall treatment protocol (T2). Nonparametric statistics were used for comparisons of starting forms and of the T1-T2 changes between the 2 treatment groups. The stainless-steel crown Herbst appliance and the Twin-block appliance produced very similar therapeutic modifications in Class II patients, although the Twin-block group exhibited almost 2 mm greater correction of the maxillomandibular differential than did the crown Herbst group. The treatment effects of both protocols led to a normalization of the dentoskeletal parameters at the end of the overall treatment period. Twin-block therapy also induced a greater increase in the height of the mandibular ramus (posterior facial height). Overall, only minor differences were detected in the treatment and posttreatment effects of a compliance-free (crown Herbst) and a noncompliance-free (Twin-block) appliance for correcting Class II disharmony.

Adolescent↗
PubMed2004

Postpubertal assessment of treatment timing for maxillary expansion and protraction therapy followed by fixed appliances.

In this cephalometric investigation, we evaluated the correction of Class III malocclusion in subjects who had attained postpubertal skeletal maturity and considered whether treatment timing influenced favorable craniofacial modifications. All subjects (n = 50) were treated with an initial phase of rapid maxillary expansion and protraction facemask therapy, followed by a second phase of preadjusted edgewise therapy. The treated sample was divided into an early treated group (early mixed or late deciduous dentition, 33 subjects) and a late treated group (late mixed dentition, 17 subjects). Mean treatment duration times were 7 years 2 months for the early treatment group and 4 years 5 months for the late treatment group. The treated patients were matched to untreated controls (early control group, 14 subjects; late control group, 10 subjects) on the basis of race, sex, mean age at first observation, mean age at second observation, mean observation intervals, and type of malocclusion. A modified version of Johnston's pitchfork analysis, with additional angular and linear measures for mandibular size and shape and for vertical skeletal relationships, was performed. Analysis of variance was used to evaluate the difference in means for each cephalometric variable in the treated groups compared with the corresponding control groups. The findings showed that orthopedic treatment of Class III malocclusion was more effective when it was initiated at an early developmental phase of the dentition (early mixed or late deciduous) rather than during later stages with respect to untreated Class III control groups. Patients treated with rapid maxillary expansion and facemask therapy in the late mixed dentition, however, still benefited from the treatment, but to a lesser degree. Early treatment produced significant favorable postpubertal modifications in both maxillary and mandibular structures, whereas late treatment induced only a significant restriction of mandibular growth. Significant changes in mandibular size were associated with significant changes in mandibular shape only in early treated subjects. The main contribution to overall occlusal correction was related to skeletal modifications rather than dental changes in both early and late treated groups.

Adolescent↗
PubMed2004

Two interceptive approaches to palatally displaced canines: a prospective longitudinal study.

This study evaluated the effectiveness of two interceptive approaches to palatally displaced canines (PDCs), ie, extraction of the deciduous canines alone and in association with the use of a cervical pull headgear. The prospective longitudinal design of the investigation included 46 subjects with PDC (62 maxillary canines) who were randomly assigned to one of three groups (1) a group that underwent the extraction of the deciduous canine only, (2) a group that received in addition the use of a cervical pull headgear, and (3) an untreated control group. Panoramic radiographs were evaluated at initial observation (T1) and after an average period of 18 months (T2). Cervical vertebral maturation was assessed on lateral cephalograms at T1. Successful or unsuccessful canine eruption was assessed 48 months after T1. The between-group statistical comparisons were performed on the T1-T2 changes in the diagnostic parameters on panoramic radiographs, the prevalence rates of successful canine eruption, and the amount of time for canine eruption. The removal of the deciduous canine as an isolated measure to intercept palatal displacement of maxillary canines showed a prevalence rate of 50% success, which was not significantly greater than the success rate in untreated controls. The use of a headgear in addition to the extraction of the deciduous canine induced successful eruption in 80% of the cases, with a significant improvement in the measures for intraosseous canine position. There was no significant difference between the two interceptive approaches in the time required for canine eruption.

Cephalometry↗
PubMed2003

Morphometric analysis of the transverse dentoskeletal features of class II malocclusion in the mixed dentition.

The aim of the present study was to evaluate the dentoskeletal features of Class II malocclusion in the transverse plane by means of a morphometric analysis (thin-plate spline analysis [TPS]) applied to posteroanterior cephalograms. A sample of 49 subjects (24 males, 25 females; mean age 7 years, 9 +/- 5 months) with Class II Division 1 malocclusion was compared with a control group of 50 subjects (17 males, 33 females; mean age 8 years, 4 +/- 3 months) with Class I occlusion. Subjects of both groups were in the mixed dentition and had no history of orthodontic treatment. Average craniofacial configurations were subjected to TPS analysis to compare the differences in shape between the two groups. The results of the present study showed that subjects with Class II malocclusion exhibited significant shape differences in craniofacial configuration in the frontal plane when compared with subjects with normal occlusion; these differences mainly consisted of a contraction of the maxilla at both the skeletal and the dentoalveolar levels and a narrowing of the base of the nose. The reduction in maxillary dentoskeletal width was associated with an increase in the vertical height of the maxilla.

Alveolar Process↗
PubMed2003

Long-term effectiveness and treatment timing for Bionator therapy.

The aim of the present investigation was to provide information about the long-term effects and optimal timing for class-II treatment with the Bionator appliance. Lateral cephalograms of 23 class-II patients treated with the Bionator were analyzed at three time periods: T1, start of treatment; T2, end of Bionator therapy; and T3, long-term observation (after completion of growth). T3 includes a phase with fixed appliances. The treated sample was divided into two groups according to their skeletal maturity as evaluated by the cervical vertebral maturation (CVM) method. The early-treated group (13 subjects) initiated treatment before the peak in mandibular growth, which occurred after completion of Bionator therapy. The late-treated group (10 subjects) received Bionator treatment during the peak. The T1-T2, T2-T3, and T1-T3 changes in the treated groups were compared with changes in control groups of untreated class-II subjects by nonparametric statistics (P < .05). The findings of the present study on Bionator therapy followed by fixed appliances indicate that this treatment protocol is more effective and stable when it is performed during the pubertal growth spurt. Optimal timing to start treatment with the Bionator is when a concavity appears at the lower borders of the second and the third cervical vertebrae (CVMS II). In the long-term, the amount of significant supplementary elongation of the mandible in subjects treated during the pubertal peak is 5.1 mm more than in the controls, and it is associated with a backward direction of condylar growth. Significant increments in mandibular ramus height also were recorded.

Activator Appliances↗
PubMed2003

Rapid maxillary expansion followed by fixed appliances: a long-term evaluation of changes in arch dimensions.

The purpose of this longitudinal study was to evaluate the short- and long-term changes in dental arch dimensions in patients treated with rapid maxillary expansion (RME) followed by fixed edge-wise appliances. The records of 112 patients in the treated group (TG) were compared with those of 41 untreated controls. Serial dental casts were available at three different intervals: pretreatment (T1), after expansion and fixed appliance therapy (T2), and at long-term observation (T3). The mean duration of the T1-T2 and T2-T3 periods for the TG group was three years two months +/- five months and six years one month +/- one year two months, respectively. Treatment by RME followed by fixed appliances produced significantly favorable short- and long-term changes in almost all the maxillary and mandibular arch measurements. In comparison with controls, a net gain of six mm was achieved in the maxillary arch perimeter, whereas a net gain of 4.5 mm was found for the mandibular arch perimeter of treated subjects in the long term. The duration of retention with a fixed lower appliance in the posttreatment period did not appear to affect the long-term outcomes of the treatment protocol significantly. The amount of correction in both maxillary and mandibular intermolar widths equaled two-thirds of the initial discrepancy, whereas treatment eliminated the initial deficiency in maxillary and mandibular intercanine widths. The amount of correction for the deficiency in maxillary arch perimeter was about 80%, whereas in the mandible a full correction was achieved.

Adolescent↗
PubMed2003

Long-term effects of Class III treatment with rapid maxillary expansion and facemask therapy followed by fixed appliances.

In this cephalometric investigation, we compared the long-term effects of an initial phase of rapid maxillary expansion and facemask (RME/FM) therapy followed by comprehensive edgewise therapy with the effects of growth in untreated, matched controls. The treated sample consisted of 34 patients who underwent RME/FM treatment before the pubertal growth spurt (average age, 8 years 3 months at the beginning of treatment). At the final observation period (average age, 14 years 10 months), all patients were in decelerative growth phases as determined by the cervical vertebral maturation (CVM) method. After the first 10 months of active treatment, significant favorable changes in both the maxillary and the mandibular skeletal components were noted. The forward movement of the maxilla was 1.8 mm greater than in the controls, mandibular projection was reduced by almost 3 mm, and the relative sagittal intermaxillary discrepancy improved by 4.3 mm, as measured by the Wits appraisal. During the posttreatment period, the treated and untreated Class III subjects generally grew similarly, although the skeletal relationship of the maxilla to the mandible remained unchanged in the RME/FM group, whereas the controls had an increased skeletal discrepancy of 3.0 mm. Over the long term, there was a slightly greater increase in midfacial length (1.6 mm) in the treatment group than in the controls. Similarly, the distance from Point A to nasion perpendicular decreased by 1.2 mm in the treated group. The overall increase in mandibular length was 2.4 mm less in the RME/FM group than in the controls, and mandibular projection relative to nasion perpendicular was 3.0 mm less in the treated group. The change in the Wits appraisal was substantial between groups (6.1 mm), with an improvement in the intermaxillary relationship in the treated group (3.4 mm); the Wits appraisal worsened (-2.7 mm) in the untreated controls. No clinically significant differences were observed between the groups in the vertical dimension. Overjet increased significantly in the treated group relative to the controls (4.4 mm), whereas the molar relationship decreased significantly (-3.9 mm). It appears that the favorable skeletal change observed over the long term is due almost entirely to the orthopedic correction achieved during the RME/FM protocol. During the posttreatment period that includes the pubertal growth spurt, craniofacial growth in RME/FM patients is similar to that of untreated Class III controls. Aggressive over-correction of the Class III skeletal malocclusion, even toward a Class II occlusal relationship, appears to be advisable, with the establishment of positive overbite and overjet relationships essential to the long-term stability of the treatment outcome.

Age Factors↗
PubMed2002

An improved version of the cervical vertebral maturation (CVM) method for the assessment of mandibular growth.

The present study aimed to provide a version of the Cervical Vertebral Maturation (CVM) method for the detection of the peak in mandibular growth based on the analysis of the second through fourth cervical vertebrae in a single cephalogram. The morphology of the bodies of the second (odontoid process, C2), third (C3), and fourth (C4) cervical vertebrae were analyzed in six consecutive cephalometric observations (T1 through T6) of 30 orthodontically untreated subjects. Observations for each subject consisted of two consecutive cephalograms comprising the interval of maximum mandibular growth (as assessed by means of the maximum increment in total mandibular length, Co-Gn), together with two earlier consecutive cephalograms and two later consecutive cephalograms. The analysis consisted of both visual and cephalometric appraisals of morphological characteristics of the three cervical vertebrae. The construction of the new version of the CVM method was based on the results of both ANOVA for repeated measures with post-hoc Scheffé's test (P < .05) and discriminant analysis. The new CVM method presents with five maturational stages (Cervical Vertebral Maturation Stage [CVMS] I through CVMS V, instead of Cvs 1 through Cvs 6 in the former CVM method). The peak in mandibular growth occurs between CVMS II and CVMS III, and it has not been reached without the attainment of both CVMS I and CVMS II. CVMS V is recorded at least two years after the peak. The advantages of the new version of the CVM method are that mandibular skeletal maturity can be appraised on a single cephalogram and through the analysis of only the second, third, and fourth cervical vertebrae, which usually are visible even when a protective radiation collar is worn.

Adolescent↗
PubMed2002

Long-term effects of rapid maxillary expansion: a posteroanterior cephalometric evaluation.

The aim of this study was to investigate long-term effects induced by rapid maxillary expansion (RME), followed by comprehensive orthodontic treatment, in a sample of 42 patients compared with normal growth changes in a sample of 20 subjects. Treated subjects underwent Haas-type RME with 2 turns a day (0.25 mm per turn) until the expansion screw reached 10.5 mm (about 21 days). The Haas expander was kept on the teeth as a passive retainer for an average of about 2 months. Immediately after the Haas expander was removed, fixed standard edgewise appliances were placed. Posteroanterior cephalograms were analyzed for each subject in both groups at T1 (pretreatment) and at T2 (long-term observation). The mean age at T1 was 11 years 10 months for both the treated and the control groups. The mean ages at T2 also were comparable (20 years 6 months for the treated group, and 17 years 8 months for the control group). The study included transverse measurements on dentoalveolar structures, maxillary and mandibular bony bases, and other craniofacial regions (nasal, zygomatic, orbital, and cranial). RME followed by edgewise appliance therapy appears to be an effective procedure to increase transverse facial dimensions in the long term, at both the skeletal and the dentoalveolar levels. Significant pretreatment deficiencies in maxillary width, maxillary incisor apex width, and maxillary first molar width remained corrected at a mean age of about 20 years. The initial deficiency in lateroorbital width was also eliminated.

Adult↗
PubMed2002

Thin-plate spline analysis of the short- and long-term effects of rapid maxillary expansion.

The aim of this study was to investigate the short- and long-term effects induced by rapid maxillary expansion (RME) on the shape of the maxillary and circummaxillary structures by means of thin-plate spline (TPS) analysis. The sample consisted of 42 patients who were compared with a control sample of 20 subjects. The treated subjects underwent Haas-type RME, followed by fixed appliance therapy. Postero-anterior (PA) cephalograms were analysed for each treated subject at T1 (pre-treatment), T2 (immediate post-expansion), and T3 (long-term observation), and were available at T1 and T3 for the control group (CG). The mean age at T1 was 11 years and 10 months for both groups. The mean chronological ages at T3 were 20 years, 6 months for the treated group (TG) and 17 years, 8 months for the control group. The study focused on shape changes in the maxillary, nasal, zygomatic, and orbital regions. TPS analysis revealed significant shape changes in the TG. They consisted of an upward and lateral displacement of the two halves of the naso-maxillary complex as a result of active expansion in the short-term, and normalization of maxillary shape in the transverse dimension in the long-term (the initial transverse deficiency of the maxilla in the treated group was eliminated by RME therapy both in the short- and long-term). At the end of the observation period, the nasal cavities were larger when compared with both their pre-expansion configuration and the final configuration in the controls. RME with the Haas appliance appears to be an efficient therapeutic means to induce permanent favourable changes in the shape of the naso-maxillary complex.

Adolescent↗