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Biomedical subjects

Lori A Sansone

Publications and source records attributed to Lori A Sansone.

12 recordsLinked to original sources
PubMed2005

An unusual cause of dizziness in bulimia nervosa: a case report.

OBJECTIVE: The current article describes the case of a 23-year-old female with purging-type bulimia nervosa who was evaluated by her primary care physician for dizziness and lightheadedness. METHODS: After laboratory studies were performed by her primary care physician, the patient was admitted to the hospital because of severe anemia. The patient had been taking nonsteroidal antiinflammatory drugs (NSAIDS) at prescribed doses for shin splints that were secondary to jogging and developed gastric erosion. RESULTS: Endoscopic examination showed that she had diffuse gastritis with linear, streaky ulcerations throughout the body of the stomach. DISCUSSION: Lightheadedness is a common clinical symptom among individuals with eating disorders, but is typically related to dehydration, malnutrition, hypometabolism, and/or combinations of these factors. Clinicians need to consider NSAID use, which may cause erosive gastritis, blood loss, and lightheadedness.

Adult↗
PubMed2003

Metoclopramide and unintended weight gain.

OBJECTIVE: This paper describes the case of a 19-year-old female with anorexia nervosa (restricting type) who was prescribed metoclopramide (Reglan, Robins, Richmond, VA) for delayed gastric emptying. She subsequently experienced dramatic and unintended weight gain. RESULTS: The initial treatment of delayed gastric emptying with metoclopramide did not result in a significant change in body weight. However, an increase in the dose resulted in a 20% increase in the patient's body weight over a 2-month period. DISCUSSION: The risks of weight gain that accompany the administration of metoclopramide are discussed, as well as the postulated etiology and psychological implications for the patient.

Adult↗
PubMed2003

Sertraline-induced hyperglycemia: case report.

Empirical studies with humans suggest that selective serotonin reuptake inhibitors (SSRIs) may, through increases in serotonergic activity, increase insulin secretion, increase insulin sensitivity, and lower serum glucose levels. Indeed, the potentially beneficial effects of SSRI treatment in diabetics are documented. However, we describe the case of a female, with diet-controlled, type 2 diabetes, whose glucose levels increased with exposure to sertraline.

Antidepressive Agents↗
PubMed2002

Assessment tools for self-harm behavior among those with eating disorders.

There appears to be a substantial minority of eating disorder patients who report self-harm behaviors. This paper reviews the available assessment tools relating to individuals with eating disorders and self-harm behaviors. Current eating disorder assessments do not contain any items relating to self-harm behaviors. Several of the self-harm measures contain some eating disorder items, but not a sufficient number to provide an eating disorder diagnosis. Among the self-harm measures, only three offer items relating to eating pathology as well as overt self-harm and high-lethal behaviors. One of the three has an established scoring that predicts borderline personality disorder. In summary, there are no currently available assessment tools that are able to simultaneously diagnose eating disorder pathology as well as measure self-harm behaviors.

Journal Article↗
PubMedDate not supplied

Patient attitudes toward weight gain with medications.

OBJECTIVE: The purpose of this study was to examine patient attitudes toward weight gain with medications under 4 conditions-medical vs psychiatric and life-threatening vs non-life-threatening. METHOD: In a suburban primary care practice, 241 patients completed surveys that explored the 4 study conditions and the amount of weight, from 0 to 20 or more pounds, willing to be gained on medication. RESULTS: Participants were willing to gain an average of 5.51 lb for a non-life-threatening medical condition, 5.37 lb for a non-life-threatening psychiatric condition, 13.30 lb for a life-threatening medical condition, and 12.70 lb for a life-threatening psychiatric condition. Participants were willing to gain significantly more weight with a medical vs psychiatric condition and with a life-threatening vs non-life-threatening condition. There were no significant gender differences in responses. CONCLUSIONS: There appear to be distinct patterns of acceptability of weight gain with medications. This information may enhance prescribers' ability to strategize medication compliance among patients.

Adolescent↗
PubMedDate not supplied

The prevalence of personality disorders among those with eating disorders.

The genuine prevalence of personality disorders among those with eating disorders is unknown. However, in this paper, we summarize the existing data, with careful acknowledgment of our approach to interpretation as well as the limitations of previous studies. Our findings indicate that obsessive-compulsive personality is the most common personality disorder in restricting-type anorexia nervosa, while borderline personality is the most common personality disorder in binge-eating/purging type anorexia nervosa. Borderline personality is the most common personality disorder in bulimia nervosa, as well. In those with binge eating disorder, obsessive-compulsive personality is the most common personality disorder although, compared with the preceding eating disorder diagnoses, there are broader clusters of personality disorders represented in this group. We discuss the implications of these findings.

Journal Article↗
PubMedDate not supplied

The use of psychotropic medications in eating disorder patients with personality disorders.

The use of psychotropic medications in eating disorder patients with personality disorders (PDs) is a complex topic. In this overview, we do not focus on individual studies, but rather on the philosophical issues and broader management principles of medications in this comorbid population. We review a general construct of personality and PD development, the theories that underlie how medications might work in PDs, and the target-symptom approach to treatment. We also discuss the essential elements of the prescribing context, an approach to psychotropic medication selection in the borderline personality population, and general caveats for medication use in those with eating disorders. Despite available data, significantly more research is needed in this area.

Journal Article↗