Three-dimensional classification of spinal deformities using fuzzy clustering.
STUDY DESIGN: A prospective study of a large set of three-dimensional (3D) reconstructions of spinal deformities in adolescent idiopathic scoliosis (AIS). OBJECTIVES: To determine the value of fuzzy clustering techniques to automatically detect clinically relevant 3D curve patterns within this set of 3D spine models. SUMMARY OF BACKGROUND DATA: Classification is important for the assessment of AIS and has been mainly used to guide surgical treatment. Current classification systems are based on visual curve pattern identification using two-dimensional radiologic measurements but remain controversial because of their low interobserver and intraobserver reliability. A clinically useful 3D classification remains to be found. METHODS: An unsupervised learning algorithm, fuzzy k-means clustering, was applied on 409 3D spine models. Analysis of data distribution using clinical parameters was performed by studying similar curve patterns, near each cluster center identified. RESULTS: The algorithm determined that the entire sample of models could be segmented in five easily differentiated curve patterns similar to those of the Lenke and King classifications. Furthermore, a system with 12 classes made possible the identification of subpatterns of spinal deformity with true 3D components. CONCLUSIONS: Automatic and clinically relevant 3D classification of AIS is possible using an unsupervised learning algorithm. This approach can now be used to build a relevant 3D classification of AIS using appropriate key features of 3D models selected by a panel of expert spinal deformity surgeons.