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Luis Resel Estévez

Publications and source records attributed to Luis Resel Estévez.

5 recordsLinked to original sources

[Effect of recipient age on transplants performed using organs from donors in asystole].

OBJECTIVES: To evaluate the influence of receptor's age on the outcomes of kidney transplants with organs from non heart beating donors. METHODS: Observational study of the historic cohort of 570 kidney transplants performed at the Hospital Clínico San Carlos between 1991 and 1999. Receptor's were divided into two age groups, group 1 younger than 50 years, and group 2 older than 50 years. All organs where harvested from non heart beating donors. RESULTS: We studied 110 kidney transplants coming from non heart beating donors; 52 belonged to group 1, and 57 to group 2. Three-year patient survival for receptor's younger than 50 years was 100%. The probability of three-year survival for receptor's older than 50 years was 79.39% (p 0.07). Graft survival was 88.46%, 86.54%, and 86.54% at 12, 24, and 36 months respectively for receptor's younger than 50 years. When receptors were older than 50 years the probability of functioning graft in the same periods of time was 89.20%, 89.20%, and 86.32% respectively. CONCLUSIONS: Receptor's age doesn't seem to influence graft survival when kidneys from non heart beating donors are used.

Adolescent↗

[Ipsilateral metanephric adenoma and clear-cell carcinoma. Personal experience and review of the literature].

OBJECTIVES: To perform an update in such an infrequent pathology and to report our own experience. METHODS: We report two new cases and review the national and international literature. RESULTS: We report two cases of ipsilateral metanephric adenoma and clear cell carcinoma. The first case, metachronous, was detected after 15 months of follow-up in a patient who underwent partial nephrectomy due to clear cell carcinoma. The second one, synchronic, was incidentally discovered in the surgical specimen. CONCLUSIONS: Metanephric adenoma is as infrequent neoplasia; its diagnosis is histological, being difficult to suspect by complementary diagnostic tests, so that most cases undergo surgical treatment in spite of its benign character.

Adenocarcinoma, Clear Cell↗

[Collecting duct carcinoma. Personal experience and review of the literature].

OBJECTIVE: To present our experience with renal collecting duct carcinoma and review the literature. METHODS: We reviewed our experience with collecting duct carcinoma of the kidney. We found 6 cases out of 176 nephrectomies (3.4%), which accounts for one of the largest series reported in the literature. The radiological, histological and immunohistochemical findings are analyzed. RESULTS: The histological and immunohistochemical findings showed a specificity for high molecular weight cytokeratins and Ulex europeaeus but the imaging findings were not distinct from those of other renal tumors. According to the anatomopathological findings, we have classified the patients into three groups with three distinct courses. All patients underwent radical nephrectomy and one patient received adjuvant therapy. CONCLUSIONS: We have identified a subgroup of low grade collecting duct carcinoma of the kidney with a particularly favorable behavior in two patients of our series. At 56 and 41 months' follow-up, both patients remain disease-free. As reported in the literature, patients with high grade and stage collecting duct carcinoma of the kidney have a poor outcome. They develop severe complications and die less than one year after the diagnosis, despite adjuvant immunotherapy.

Aged↗

[Clinical research in urology and scientific methodology].

Clinical epidemiology is the science and method of studying the optimal decisions in clinical medicine, taking into consideration the epidemiological characteristics of the patient and his/her external clinical environment, the disease involved, and factors and procedures to which the patient is exposed in his/her clinical environment, specially clinical actions. Research should be a systematic process, organized and objective, aimed to answer the question posed. Systematic means that the scientific method is applied, for that a hypothesis or work objective is formulated from observations or established knowledge about a topic, data are collected following a pre-established design, and, once analyzed and interpreted, conclusions are obtained which will modify or add new knowledge to the previous, and a new cycle starts again. Organization means that all members in the research team know perfectly what to do during the whole study, apply the same definitions and criteria to all participants, and act in identical way in front of any doubt. To achieve this, it is mandatory to write a protocol specifying all details related to the study. The meaning of the word objective is that conclusions obtained are not based on subjective impressions but on facts that have been observed, measured, and analyzed, and that any prejudice the study responsibles could have is avoided during its interpretation.

Biomedical Research↗