Biomedical subjects

Lydia Makrides

Publications and source records attributed to Lydia Makrides.

3 recordsLinked to original sources

PubMed2004

Longitudinal changes in exercise capacity after stroke.

OBJECTIVE: To determine if stroke patients without specific aerobic training experience a change in the first 6 months after stroke. DESIGN: Descriptive, longitudinal study with repeated measures of exercise capacity at 1, 2, 3, and 6 months after stroke. SETTING: Exercise testing laboratory in a tertiary care hospital. PARTICIPANTS: Consecutive sample of 25 patients (mean age +/- standard deviation, 64.1+/-13.6 y) 1 month after first ischemic stroke. INTERVENTIONS: Not applicable. Main Outcome Measures Peak oxygen consumption (Vo(2)peak) was measured by open-circuit spirometry during maximal effort treadmill walking with 15% body-weight support. RESULTS: Mean Vo(2)peak increased from 14.8+/-5.3 mL x kg(-1). min(-1) at 1 month to 17.3+/-7.0 mL x kg(-1).min(-1) at 6 months after stroke (P=.003) or from 61.7%+/-16% to 71.3%+/-23% of age- and sex-related normative values for sedentary healthy adults (P=.008). CONCLUSIONS: Despite improvements in Vo(2)peak and other indices of cardiovascular training between 1 and 6 months poststroke, substantial limitations in exercise capacity persisted. Further study is needed to determine the extent to which these limitations can be modified through aerobic conditioning.

Age Factors↗

PubMed2002

Cardiovascular stress during a contemporary stroke rehabilitation program: is the intensity adequate to induce a training effect?

OBJECTIVES: To investigate the level of cardiovascular stress of physical therapy (PT) and occupational therapy (OT) sessions of a contemporary stroke rehabilitation program and to identify therapeutic activities that elicit heart rate responses adequate to induce a training effect. DESIGN: A descriptive, longitudinal study with heart rate and activity monitoring of PT and OT sessions at biweekly intervals, 2 to 14 weeks poststroke. SETTING: An acute inpatient stroke unit and inpatient and outpatient stroke rehabilitation units. PARTICIPANTS: A consecutive sample of 20 patients with ischemic stroke who participated in inpatient and outpatient stroke rehabilitation. INTERVENTION: Observation of routine PT and OT sessions for patients poststroke without influencing the extent and content of the sessions. MAIN OUTCOME MEASURE: Time per session in which heart rate was within the calculated target heart rate zone. RESULTS: Time per PT session spent in target heart rate zone was low (2.8+/-0.9 min), and per OT session was negligible (0.7+/-0.2 min) over the course of rehabilitation. CONCLUSIONS: The PT and OT sessions between 2 and 14 weeks poststroke did not elicit adequate cardiovascular stress to induce a training effect.

Adult↗

PubMed2002

Exercise capacity early after stroke.

OBJECTIVE: To evaluate exercise capacity of patients with a poststroke interval of less than 1 month. DESIGN: Prospective, cohort, observational study. SETTING: Exercise testing laboratory in a tertiary care hospital. PARTICIPANTS: Twenty-nine patients (mean age +/- standard deviation, 64.9+/-13.5 y) with a poststroke interval of 26.0+/-8.8 days. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Peak exercise capacity (VO(2)peak) was measured by open-circuit spirometry during maximal effort treadmill walking with 15% body-weight support. RESULTS: Mean VO(2)peak was 14.4+/-5.1 mL. kg(-1). min(-1) or 60%+/-16% of age- and sex-related normative values for sedentary healthy adults. CONCLUSIONS: Exercise capacity approximately 1 month after stroke was compromised. Further research is needed to elucidate the physiologic basis of this low capacity.

Exercise Test↗