Lyn A Thet | PubMed Health

PubMed2003

Hemoglobinopathy case finding by pulse oximetry.

Pulse oximetry is a widely used, noninvasive instrument for monitoring oxygen saturation. Its use, however, is limited in the setting of dyshemoglobinemias. We report a case of hemoglobin Rothschild in an Asian patient diagnosed as a result of routine pulse oximetry. This case reiterates the limitations of pulse oximetry in patients with dyshemoglobinemias, while introducing its use as a case-finding tool for such conditions.

Diagnostic Tests, Routine↗

PubMed2003

Purulent pericarditis induced by endobronchial needle injection of adenoviral-mediated gene therapy.

A case of a 65-year-old man who presented with cardiac tamponade and was diagnosed with Staphylococcus aureus purulent pericarditis is reported. The patient had recently undergone bronchoscopic endobronchial needle injection of gene therapy for recurrent lung cancer. It was felt that incidental, direct inoculation of contaminated contents into the pericardium, versus mediastinal seeding with direct extension, had occurred. Following pericardiocentesis and antibiotic therapy, the patient fully recovered. The present case is the first reported incidence of purulent pericarditis induced by bronchoscopic injection of gene therapy.

Adenoviridae↗