PubMed Health⌕ Search

Biomedical subjects

M A Abdullah

Publications and source records attributed to M A Abdullah.

At least 37 records · Page 2Linked to original sources

Effect of different polymerization techniques on dimensional stability of record bases.

In this study, discrepancies in the adaptation of the posterior borders of maxillary record bases to their casts were analyzed with five polymerization techniques: (1) bench curing, (2) curing under a coat of petroleum jelly, (3) curing in a monomer atmosphere, (4) curing under air pressure, and (5) curing under warm water and air pressure. Ten record bases were made with each of the five techniques and were tested immediately for dimensional accuracy. Measurements of adaptations were made at three points that represent the right and left crest of the ridge and midpalatal region with a measuring microscope equipped with a filar unit-measuring eyepiece. Dimensional changes were observed under all test conditions. The monomer atmosphere technique produced the least dimensional change when compared with other techniques.

Acrylic Resins↗

Predation of Acacia seeds by bruchid beetles and its relation to altitudinal gradient in south-western Saudi Arabia.

The distribution of the Acacia trees and their bruchid seed beetles in south-western Saudi Arabia revealed that each of the host-insect pair occupied a specific range along the altitudinal gradient from sea level to 2500 m. At low to intermediate altitudes, between sea level and 1750 m, at hot to worm environments, the following host-insect pairs were recorded: Acacia asak--Bruchidius. sp., A. ehrenbergiana--B.saudicus, A.hamulosa--B.sp., A.oerfota--B.sp., A.seyal--B. sp., A.tortilis--B. aurivilli and A.tortilis--B. sahelicus. At high altitudes between 1750 and 2500m, at cool environment the following host insect pairs were recorded: A.negrii--B.arabicus and A.gerrardii--B.arabicus. The rate of seed predation varied among Acacia spp., but the highest were recorded in A. tortilis and A. ehrenbergiana.

Acacia↗

Traditional practices and other socio-cultural factors affecting the health of children in Saudi Arabia.

The medical services in Saudi Arabia have improved tremendously over the last two decades, and health centres are easily accessible to more than 93% of the population. Nevertheless, folk medicine, including cautery, bone setting, manual tonsillectomy, uvulectomy, use of herbal medicines and use of harmful teething powders, in addition to religious healing, is widely practised. Reasons include influence of grandparents, religious beliefs and failure of modern medicine to find an answer to some chronic disorders. These problems, and measures to counteract them, are discussed. Attention is also drawn to some of the harmful 'imported' practices that are affecting the health of children, including smoking, children driving cars and problems resulting from dependence on housemaids to bring up children. Some nutritional beliefs and taboos are also mentioned.

Adolescent↗

Pulmonary alveolar microlithiasis in a Saudi child and two cousins.

Pulmonary alveolar microlithiasis is a rare disease and only 32 cases have been reported in children under 12 years of age. The first report on Saudi children with this disorder and on affected cousins is presented, supporting the possible hypothesis of it being an autosomal recessive disorder. The importance of differentiating it from other conditions, particularly pulmonary tuberculosis, and the current approach to diagnosis and management are discussed.

Calculi↗

Glucose-galactose malabsorption with renal stones in a Saudi child.

A case of glucose-galactose malabsorption in an 18-month-old Saudi girl is presented. She had associated bilateral renal stones with impaired renal function. Dietary therapy improved her malabsorption and the renal stones were cleared by extracorporeal shortwave lithotripsy.

Carbohydrate Metabolism, Inborn Errors↗

Ambiguous genitalia: medical, socio-cultural and religious factors affecting management in Saudi Arabia.

Twenty-eight children with ambiguous genitalia were seen at King Khalid University Hospital over a 6-year period. The incidence of this disorder was 0.4/1000 live births. Of the total, 21 (75%) were Saudis and seven (25%) were non-Saudis. The consanguinity rate was 67.9%. Twenty-four (85.7%) were born in hospital and four (14.3%) at home. In only three (10.7%) was the news first broken to the parents by a senior doctor, in 13 (46.4%) by a junior doctor, and in 11 (39.3%) by a nurse. Ambiguous genitalia were observed in 22 (78.6%) at birth and in six (21.4%) were picked up later. Owing to a lack of immediate investigative facilities and for some socio-cultural reasons, 19 of the latter groups were assigned sex without prior investigations. There was an obvious preference to assign male sex. On investigation, 13 (46.4%) had XX chromosomes, 11 (39%) XY and one (3.6%) XO: in three (10.7%), chromosomal results were not available. There were 14 cases (50%) of congenital adrenal hyperplasia, two of 5-alpha reductase deficiency (7.1%), and five of testicular feminization syndrome (17.9%), in addition to others. After investigation, five (17.9%) of the children needed sex reassignment. This was accepted by two and rejected for socio-cultural reasons by three. The opinion of the religious leaders was obtained. Some recommendations on management of these cases are made, based on our local experience.

Disorders of Sex Development↗

Horseshoe lung: differential diagnosis.

A detailed radiologic and anatomic study of one horseshoe lung syndrome has already been published from this centre. A further case of horseshoe lung, which was also diagnosed prospectively by radiology, is described. Alongside, this is a set of a group of three conditions: we describe a right accessory lung with a peculiar feeding arterial branch originating from the left basal pulmonary artery. The bronchogram and oesophagogram of this case were normal. The other is a case of bridging bronchus where the left lower lobe bronchus originates from the right main stem bronchus. This was discovered at post mortem bronchogram performed on a 19 weeks foetus. Finally, in the dog, we found that the pulmonary angiogram and bronchogram display close similarity to human horseshoe lung though the dog has two separate lungs. The common denominator of all above cases is the presence of a pulmonary arterial branch or bronchus crossing the midline from the ipsi to the contralateral side. Therefore, it may be concluded "in contradiction to the common belief" that pulmonary angiography or bronchography alone is not sufficient for the diagnosis of horseshoe lung. When only one of these investigations is available, computerized tomography is necessary to show the isthmic lung tissue before the diagnosis of horseshoe lung is confirmed.

Animals↗

Beta-adrenergic receptor blockade in the management of pregnant women with mitral stenosis.

Twenty-five pregnant women with symptomatic mitral valve stenosis (mean valve area, 1.1 +/- 0.25 cm2) were managed by initiation or modification of beta-adrenergic receptor blockade with the use of either propranolol or atenolol. Significant improvement of symptoms occurred in 23 patients (92%) (p less than 0.01); the mean maternal heart rate was reduced significantly from 86 +/- 4 to 78 +/- 5 beats/min (p less than 0.0001). The overall fetal heart rate ranged between 130 to 150 beats/min during treatment. Only two patients required urgent closed mitral valvotomy, after pulmonary edema developed as a result of poor compliance to beta-blockade. All patients were safely delivered of infants at term. Fetal heart rates ranged between 120 to 140 beats/min at delivery. There was no maternal or fetal death. Pregnant woman with symptomatic mitral valve stenosis can be safely managed with beta-blockade, giving significant reduction in the incidence of pulmonary edema with no unwanted neonatal side effect.

Adrenergic beta-Antagonists↗

Antithyroid and other organ-specific antibodies in Saudi Arab diabetic and normal children.

Sera from 162 Saudi Arab children were examined for autoantibodies to thyroid microsomes, thyroglobulin pancreatic islet cells, gastric parietal cells, and adrenocortical cells. The subjects included a control group (n = 76) and 86 children below 14 years with Type 1 diabetes. Antithyroid antibodies were detected in 8.1% of the diabetic group and in none of the control group. Parietal cell antibodies were found in 9.3% of the diabetic group and 4.4% of the control group; 14.6% of diabetic children and 2.2% of control children were positive for islet antibodies. However, 56.3% (9/16) of those who were tested at onset of diabetes had positive islet antibodies. In none of the children could we detect adrenocortical cell antibodies.

Adolescent↗

Lead concentrations in maternal and cord blood in women users of surma eye cosmetics.

A prospective study was undertaken to analyse the lead concentrations in maternal and cord blood of 71 pregnant Arab women at term who used eye cosmetics, particularly "surma". A total of 64 mothers (90%) used eye cosmetics throughout pregnancy, and, of these, 45% used surma. The lead content of the cosmetics available in the market was found to vary between zero and 88%. The mean lead concentrations in all blood samples were higher than the accepted natural levels of 0.001 mumol/l, but lower than the subtoxic level of 1.9 mumol/l. The mean lead concentration of all samples was lower than the subtoxic level of 1.9 mumol/l but higher than that quoted in the literature and suggested to be a natural level (0.001 mumol/l). This indicates that other lead pollutants may be involved. Lead concentrations in maternal and cord blood correlated well, but did not show any significant difference between surma and non-surma users. None of the newborns showed apparent congenital anomalies and their birthweights were comparable to average Saudi birthweights.

Birth Weight↗

Fever in children: diagnosis and management by nurses, medical students, doctors and parents.

Thirty-six nurses, 18 final year medical students, 24 doctors and 36 parents were questioned about their understanding and management of the symptom "fever". There was an obvious tendency to over-diagnose fever by the nursing and medical staff. Antipyretics and sponging were unnecessarily prescribed. Most parents do not have a thermometer and have minimal understanding of fever and its management, and 37% regard fever as a cause of brain damage. Their main sources of information on the subject derive from relatives and friends: only 9% mentioned nurses or doctors as their source of information. Medical students receive little teaching on fever. It is recommended that more time should be devoted to teaching nurses, medical students and junior doctors about fever and they in turn should educate parents on the subject.

Adult↗

BCG lymphadenitis: a report of eight cases.

An increase in incidence of regional lymphadenitis following BCG vaccination of newborns at King Abdel Aziz University Hospital, Riyadh has been observed. Eight cases are described. One case also had infraclavicular gland enlargement. The only change in routine was the introduction of a Japanese strain of BCG. It is suggested that this might be a cause for the increase in the condition. All patients were given isoniazid. Discharge and scar formation followed aspiration in five cases, whereas in the two cases subjected to surgical excision there was uncomplicated healing. It is suggested that the latter combined with antituberculous therapy may be a more satisfactory form of treatment.

BCG Vaccine↗

Pyogenic liver abscess in children: a report of three patients and review of the literature.

Three children with pyogenic liver abscess seen over a period of 2 years are reported. Their immune status was normal and no underlying causes were detected. The clinical picture was characterized by fever, abdominal pain and tender hepatomegaly. Abscesses were solitary in two children and multiple in the third. One child died within 12 h of admission, the other two recovered completely. Recent literature on pyogenic liver abscess is reviewed.

Child↗

Size at birth of live-born Saudi infants.

Anthropometric measurements were done on 967 singleton live-born Saudi infants of gestational age 33 to 42 weeks who belonged to the high and middle social classes and who were born consecutively in Riyadh University Hospital. The 914 infants born at term (greater than or equal to 37 weeks) had a mean birthweight of 3.31 kg (SD 0.45), a mean length of 49.74 cm (SD 2.5) and a mean head circumference of 34.4 cm (SD 1.4). Values were significantly higher in males than females. Effect of sex in this study was not apparent until 40 weeks and later. Difference in body size was significant between the first-born and second infants but the trend was unimpressive with greater parity. Fifty-three (5.5%) of the infants were born preterm. Twenty-one of the preterm babies and 18 of the term infants weighed less than 2500 g, an overall incidence of low birthweight of 4%. Results were compared with studies from Saudi Arabia and other countries. It is concluded that there was no significant difference between birthweights of upper-class Saudis and Europeans.

Birth Weight↗

Seroepidemiology of rubella in Saudi Arabia: an adapted vaccination policy.

Rubella haemagglutination antibodies were tested for in sera of 1793 unvaccinated subjects with age ranging from birth to 40 years. This was to assess the immune status of the population and to see the feasibility of introduction and the proper age for rubella vaccination in a Saudi community. Those with titres of greater than or equal to 1:8 were considered as seropositive. The lowest level of antibodies was seen among the 10-18 month age group. All children aged 2-5 years were seropositive as were 75% of the elementary school girls. Only 90-95% of the women of childbearing age were seropositive, however, leaving an immune gap of 5-10%. Unnecessary mass vaccination of young children is discouraged. Rubella vaccine should be given to all final elementary school girls and all women of childbearing age after screening, whenever possible. Special catchment zones are suggested for the latter group. Further nationwide seroepidemiological surveys are recommended for the other parts of the Saudi Kingdom.

Adolescent↗

Lead poisoning among children in Saudi Arabia.

Six Saudi children aged between 10 and 30 months were found to have lead poisoning. Two of them presented with encephalopathy. Twenty children with unexplained convulsions, some of whom died, were reported to have been admitted to the local district hospital recently. All our cases were diagnosed within 2 weeks of diagnosing the index case. The source of lead was found to be a locally used teething powder known as 'Saoott' and 'Cebagin'. This was prescribed by a traditional healer. The lead content of this powder was found to be 51%. Chemical analysis of other locally used eye cosmetics and teething medicines showed a lead content of up to 88%. The difficulties faced in diagnosis and managements of these cases in developing countries are discussed. The importance of prevention is stressed.

Brain Diseases↗