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Biomedical subjects

M A Aleem

Publications and source records attributed to M A Aleem.

At least 19 recordsLinked to original sources

Primary antiphospholipid syndrome presenting as pseudobulbar palsy in a young male.

Antiphospholipid antibody syndrome (APS) is now recognized as an important risk factor for young stroke. Recurrent stroke seems to be common in patients with APS and a first stroke, recurrent stroke and vascular dementia are feared consequences of APS. We are reporting a case of primary APS with recurrent stroke presenting as pseudobulbar palsy in an young man.

Adult↗

Separation of beta- and gamma-tocopherols in serum by high performance liquid chromatography.

A simple and sensitive high performance liquid chromatographic method for the analysis of tocopherols (alpha, beta, gamma and delta) in serum with UV detection is described. In normal phase mode excellent separation of positional isomers (beta and gamma) was achieved by adjusting the proportion of isopropanol in the mobile phase. Detection limits for both beta and gamma were 0.62 mg/L and 0.42 and 1.2 mg/L for alpha and delta isomers, respectively. Measurement of all the tocopherol structural isomers (alpha, beta, gamma and delta) in a sample required only 400 microL of serum and each run was completed in less than 22 min.

Chromatography, High Pressure Liquid↗