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Biomedical subjects

M A Aliev

Publications and source records attributed to M A Aliev.

At least 19 recordsLinked to original sources

[Surgical approach in bilateral and combined echinococcosis of the lung].

One hundred and two patients aged from 4 to 65 years with echinococcosis were treated. Solitary cysts in both lungs were diagnosed in 69 patients, multiple cysts -- in 33 patients. In 10 cases small and middle cysts were in the upper parts of both lungs. These patients underwent one-stage operation consisting in lateral thoracotomy, removing of the cyst from one lung, incision of retrosternal mediastinal pleura, removing of the cyst from the second lung, drainage of pleural cavity. Fifteen patients with combined echinococcosis of the upper lobe of the right lung and liver were operated with another one-stage surgical method through thoracotomy in the third and sixth or seventh intercostal space. These methods are characterized by low traumaticity, decreased number of postoperative complications and hospital stay.

Adolescent↗

[Adequate gas exchange in two-sided and combined surgeries on thoracic and abdominal organs].

Method of combined artificial lung ventilation during simultaneous two-sided operations on the lungs was studied in 60 patients. This method is based on traditional ALV with parameters calculated according to functional state of the patient's respiratory system, and additional high-frequency jet pulmonary ventilation. The developed method was not accompanied by any severe disorders of gas exchange and mechanics of ventilation.

Abdomen↗

[Reconstructive-reparative surgeries on the esophagus in burn cicatricial strictures].

Esophagoplasty was performed in 196 patients. Combined disease of the esophagus and stomach was in 71 patients. Esophagogastroplasty was performed in 122 patients, including 104 with gastric tube, 12 -- with whole stomach, 6 -- by means of lengthening of whole stomach. Insufficiency of cervical anastomosis was revealed in 17.2% cases. Long-term results (from 6 months to 9 years) were studied in 77.9% patients. Lethality was 4.2%. Esophagocoloplasty was performed in 74 patients. Insufficiency of cervical anastomosis was seen in 14.5% cases. Long-term results (from 5 months to 9 years) are available in 87.8% patients. Lethality was 4.1%.

Burns↗

[Transbiliary interventions under videolaparoscopic control].

Transbiliary interventions under videolaparoscopic control were performed in 203 patients with benign diseases of bile ducts, in 78 of them the procedures were of purely diagnostic character. Laparoscopic microcholecystostomy was fulfilled in 117 patients. In 11 of them no desirable results were obtained. All of them had been operated upon for emergency indications. In the "cold" period operations were performed on 88 patients.

Aged↗

[Migration of the fragment of the subclavian catheter: diagnosis and surgical treatment].

Results of examination and surgical treatment of 68 patients after migration of foreign body (fragment of catheter) into venous bed were analyzed. Ultrasonic examination including transesophageal echocardiography was the main method of diagnosis. Various surgical approaches were used depending on localization of the foreign body. Policy of surgical treatment was developed. A case is reported.

Adult↗

[The use of low-molecular heparins in reconstructive surgery of ascending aortic aneurysms].

This paper analyzes the results of the use of enoxaparin for anticoagulant therapy in reconstructions on the ascending aorta (AA) as compared to unfractionated heparin applied previously in the control group. Between 1986 and 2003 a total of 30 patients with AA aneurysms were operated on at the clinic. Insufficiency of the aortic valve with degree II-III regurgitation was present in 25 (83.3%) cases. Chronic dissection of the AA was identified in 10 (33.3%) cases. The patient's age varied from 24 to 52 years (mean 39 years). The etiological factors of AA aneurysm were: Marfan's syndrome (46.7% of cases), Erdheim's syndrome (26.7%), atherosclerosis (10.0% of cases); previous chest traumas were recognized in 16.6% of patients. All the patients were operated on under extra-corporeal circulation and moderate hypothermia. The patients were distributed into two groups. In the control group, eighteen patients were operated on. Anticoagulant therapy was carried out using unfractionated heparin i. v. in a daily dose 10-15 thousand units. Heparin injection was initiated on the first postoperative day and continued for 6.5 days on the average, with a progressive change over to the use of indirect anticoagulants. In the basic group, twelve operated patients were administered the anticoagulant enoxaparin s.c. in a daily dose 0.7-1.0 mg/kg bw. Enoxaparin therapy was initiated from the first postoperative day and continued for 8.9 days on the average, with a progressive change over to indirect anticoagulants. The postoperative lethality in the control group accounted for 22.2% (4 patients). In two cases, it was induced by heart failure and in two cases, by hemorrhagic complications. In the basic group, the beneficial results were achieved in 91.7%; no hemorrhagic complications were recorded. The data obtained allow the conclusion that the use of enoxaparin significantly facilitates the postoperative management of patients with AA aneurysms, providing for a controllable and safe anticoagulant effect.

Adult↗

[Hepatic echinococcosis and its surgical treatment].

973 patients were operated for the period of 14 years for echinococcosis of the abdominal cavity. Echinococcosis of the liver was revealed in 742 (76.2%) patients. Complicated forms of echinococcosis were registered in 42.3% patients. Suppurative cyst was detected in 138 (43.9%) patients; perforation of the cyst into free abdominal cavity--in 22 (7%), into pleural cavity--in 14 (4.5%) patients, into bile ducts--in 62 cases (19.7%); biliary tracts compressing by the cyst with mechanical jaundice--in 29 (9.2%) patients; bilio-pulmonary bronchial fistula was revealed in 7 (2.3%) patients and calcification of the cysts--in 42 (13.4%). Radioisotope scanning, X-ray, ultrasound, Computed tomography and serological reactions were used for diagnosis. For differential diagnosis of parasitic cysts from non-parasitic cysts laparoscopic video technique was also used in three cases. Radical operations were carried out in 47 patients, 19 patients from them underwent total pericystectomy and 28 patients underwent resection of the liver. For echinococcosis of the liver complicated by mechanical jaundice: in this case echinococcectomia was done with the correction of the continuity of the bile duct. Ultrasound cavitation, CO2 laser, thermal or thermic means (70 degrees C solution of furaciline or instant steam treatment) were used for antiparasitic purposes.

Echinococcosis, Hepatic↗

[Optimization of diagnosis and methods of liver resection in alveolar echinococcosis].

36 resections of the liver were carried out. 66.7% of them were hemihepatectomies and extended hemihepatectomies due to sever parasitic lesions of the liver parenchyma. During resections of the liver ultrasonic scalpel and high frequency electrocoagulation, compression of the hepatoduodenal ligament under the control of the intraoperative sonography were performed. In 4 patients (11.1%) complications were observed: hepatic insufficiency (2 cases), injury of inferior vena cava (1 case) and infrahepatic abscess (1 case). Lethality made up 3.8% (1 patient died due to development of acute hepatic insufficiency after extended right-sided hemihepatectomy.

Adolescent↗

[The diagnosis and surgical treatment of cavernous hemangiomas of the liver].

The authors have examined 80 patients with cavernous hemangiomas. The disease was diagnosed on the basis of an ultrasonic investigation, computed tomography and laparoscopy. Solitary hemangiomas were diagnosed in 78 patients, multiple ones in 2. In 64 patients the size of hemangiomas was more than 5 cm, in 16 patients they were less than 5 cm. Radical resections of the liver were made in 32 patients (59.3%), palliative--in 22 patients (40.7%). Complications after the liver resections took place in 15.5% of the patients, lethality was 6.2%. Complications following the palliative operations were noted in 72.7% of the patients, lethality was 9%.

Adult↗

[Morphologic changes in the esophagus in chronic hemodialysis and after kidney transplantation].

Oesophageal biopsies were studied in 80 patients with terminal stage of chronic kidney failure (CKF) treated with programmed hemodialysis and in 27 kidney transplant recipients. The following changes in the oesophagus were found: chronic oesophagitis, degenerative changes (oedema with balloon degeneration), intercellular oedema with formation of cavities filled with oedematous liquid, calcium deposits in the mucosa and submucosa. Degenerative changes occur more frequently in patients treated with hemodialysis and soon after the kidney transplantation. This can explain more frequent occurrence of Mallori-Weiss syndrome and erosions and ulcer of the oesophagus at CKF.

Adolescent↗

[The characteristics of suppurative wounds treated with xenogenic splenic homogenate].

The authors discuss the results of treatment of 60 patients with persistent purulent wounds by applications of pig spleen homogenate (30 patients) and by the commonly accepted method (30 patients). The cytologic and microbiological data studied during the course of the wound process in both groups are analysed. The terms of cleansing, regeneration, and epithelialization of the wound surface were analysed comparatively; they were found to be 1.5 times shorter in treatment with a homogenate of xenogeneic spleen. It was thus established that a pig spleen homogenate produces a good antiinflammatory and necrolytic effect and absorbs the detritus, microbes, and toxins.

Animals↗

[The effect of high-altitude ecological and experimental stresses on the thrombocyte-vascular wall system].

Experiments in animals (rats) and examinations of the population of high-altitude shepherds were used to study the functional system "Thrombocytes-Vessel Wall" (STVW) for evaluation of the organism ecological adaptation to "pure" high-altitude stress, with and without combination with experimental-adrenergic cardionecrosogenic stress (ACNS, in rats). The adaptive increase of antiaggregation prostacyclin activity of the aorta in rats and PGI2 reaction of vessels in human population of high-altitude in mountains (2000, 3000-3500 m) were found to be a common biologist regularity. The adaptive increase of coronary reserve of the heart and vasodilatator-antiaggregation status in high-altitude shepherds correlated with an increase of antiaggregation activity of the aorta and decrease of spontaneous aggregation of the thrombocytes in rats under conditions of more prolonged adaptation to high-altitude ecological stress.

Adaptation, Physiological↗

[Prostacyclin-thromboxane imbalance after adrenergic damage of the heart and aorta and its correction with calcium antagonist finoptin and the adaptation to high-altitude climate].

Adrenergic cardiac and aortic lesion was reproduced by using intramuscularly a stress-necrogenic epinephrine dose of 2 mg/kg. Following 24 hours, the levels of malonic dialdehyde (MDA) as a TxA2 marker, were measured in the platelets. The antiaggregability of the aortic wall where PGI2 is synthesized was also examined. The adrenergic lesion was found to impair the platelet function-vascular wall balance, creating the condition for enhancing spontaneous platelet aggregation. This led to 50% death of experimental "lowland" rats. The short-term high-altitude adaptation failed to substantially modify the death rates in adrenergic lesion, though the platelets showed a 30% decrease in MDA generation. The combination of high-altitude adaptation and the calcium antagonist finoptin completely prevented the stress-induced increase in the platelet generation of MDA, a TxA2 marker, which was followed by a drastic reduction (16.6% versus 50%) in sudden death cases among the rats during adrenergic cardiac and aortic lesion.

Adaptation, Physiological↗