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Biomedical subjects

M A Alvarez

Publications and source records attributed to M A Alvarez.

58 records · Page 4Linked to original sources

[Subclinical attention changes in transient ischemic attacks in the vertebrobasilar region].

INTRODUCTION: A significant number of patients who have had cerebrovascular illness apparently recover their former abilities completely but return to normal life with subtle cognitive deficits which may affect their daily lives. Such is the situation of patients with transitory ischemic accidents who present with sustained, undiagnosed attention deficits. OBJECTIVES: To identify subclinical alterations due to attention deficits in patients with transitory ischemic accidents, and to contribute to the study of the physiopathological mechanisms involved in the integration of this function. PATIENTS AND METHODS: We examined 44 persons, divided into three groups for this study: one group had vertebro-basilar transitory ischemic accidents, a second group had supratentorial infarct and a third was healthy. All were given a specially designed computerized test of continuous work to evaluate the sustained attention component. RESULTS: Significant differences were found between the transitory ischemic accidents and healthy groups, regarding the variables including correct answers, omissions and indications of attention. This was not seen with the variables involving reaction time and number of errors. This demonstrated the existence of attention disorders involving omission in the group of patients with transitory ischemic accidents. CONCLUSION: These findings suggest the hypothesis that in the vertebro-basilar region there are important mechanisms involved in the process of sustained attention.

Acute Disease↗

Psychological characterization of testicular feminization syndrome.

Ten cases with testicular feminization syndrome (TFS) diagnosed at the National Institute of Endocrinology and Metabolism, were studied. The patients were interviewed and subjected to the following psychological tests: Raven's Progressive Matrices, the MMPI, the 16PF, and the TAT. Laboratory determinations included: nuclear chromatin, karyotype, FHS, LH, estradiol, testosterone and nitrogen retention test. Intellectual achievement was found normal, and as far as psychological stability is concerned (MMPI) there was no common profile typical of the group. Psychosexual attitudes showed alterations related to acceptance of body image, fears to be unable to maintain the stability of the couple, and lack of a strong maternal drive. Personality profile manifested two outstanding traits in the group: Dominance (E+) and Shrewdness (N+), the former being remarkably high for a female population. A hypothesis is advanced in regard to the psychological alterations of the possible role of partial androgenization of the central nervous system in these patients.

Adolescent↗

[Psychological characteristics of Cushing's syndrome].

Psychological state of 15 patients with Cushing's syndrome was studied, including 8 subjects with bilateral adrenocortical hyperplasia, 4 with adrenocortical adenoma, 2 with hypophyseal adenoma and 1 with adrenocortical cancer. The weakened intellect was noted in patients, suffering from adrenocortical hyperplasia. Low emotional stability, anxiety, suspiciousness and hesitation were characteristic of the patients under study. Psychic stability was lowered. A possible role of endogenous and exogenic factors of depression, as well as the conditions of hospitalization for such patients are discussed.

Adenoma↗