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Biomedical subjects

M A Andersen

Publications and source records attributed to M A Andersen.

5 recordsLinked to original sources
PubMed1990

Familial benign hypercalcaemia: hypercalciuria and hypocalciuria in affected members of a small kindred.

Familial benign hypercalcaemia has also been termed familial hypocalciuric hypercalcaemia because a major feature of this condition has been a relative hypocalciuria in relation to the hypercalcaemia, such that the calcium to creatinine clearance ratio is less than 0.016. The following is a report of a small kindred of patients with familial benign hypercalcaemia in which two of the affected members have frank hypercalciuria.

Adult↗
PubMed1989

Analysis of parathyroid hormone in bovine parathyroid cysts.

Parathyroid cysts were found in 2-5% of beef steers and heifers while collecting parathyroids at a local abattoir. The cyst fluid contained parathyroid hormone (PTH), averaging 15 ng/ml of fluid. Reversed-phase high-performance liquid chromatographic (HPLC) analysis of the fluid using an acetonitrile-trifluoroacetic acid solvent system, followed by carboxyl-terminal specific PTH radioimmunoassay of the eluant fractions, revealed two major peaks of PTH immunoreactivity. The first eluted at approximately 25% acetonitrile, a position similar to the commercially available human carboxyl terminal fragment of PTH-(39-84). The second peak, at approximately 37% acetonitrile, corresponded to the elution position for bovine PTH-(1-84). The cyst fluid was tested for enzyme activity by incubation of 125I-labeled bovine PTH with cyst fluid for 30 minutes at 37 degrees C, which resulted in no fragmentation of the labeled peptide. Immunohistochemistry of the cells lining the parathyroid cyst indicated that they contained PTH.

Animals↗
PubMed1989

Bone resorption.

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Animals↗
PubMed1987

Effect of lasalocid on weight gains, ruminal fermentation and forage intake of stocker cattle grazing winter wheat pasture.

Fifty fall-weaned heifers with initial weights of 209 kg (yr 1) and 222 kg (yr 2) were used to determine effects of lasalocid on weight gains, forage intake and ruminal fermentation of stocker cattle grazing winter wheat pasture. The heifers grazed a single wheat pasture for about 100 d each year, and were individually fed 1.06 kg of supplement (6 d/wk) pro-rated to supply 0, 100 or 200 mg lasalocid.head-1.d-1. Also, eight mature Hereford steers with large rumen cannula were used to evaluate further effects of lasalocid (0 or 300 mg) on ruminal fermentation during two grazing periods (immature and mature wheat forage) of yr 2 and an additional third year. Daily gains of heifers fed 200 mg lasalocid/d were .11 kg greater (P less than .05) than those of heifers fed 0 or 100 mg lasalocid/d. One hundred milligrams lasalocid did not increase weight gains. Digestibilities of forage dry matter (DM) and organic matter (OM) were similar (P greater than .05) among treatments, and lasalocid did not affect (P greater than .10) forage intake. Ruminal ammonia concentrations (10.57, 15.22 and 17.81 mg/dl +/- 1.71) were increased (P less than .05) by both levels of lasalocid in yr 1, but differences among treatment means of 8.32, 11.95 and 11.66 (SE +/- 1.44) were not significant in yr 2. Lasalocid did not consistently affect total volatile fatty acids concentrations. The acetic:propionic acid ratios in heifers were not different (P greater than .05) among treatments, but were decreased (P less than .10) by lasalocid in cannulated steers.(ABSTRACT TRUNCATED AT 250 WORDS)

Animal Feed↗