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Biomedical subjects

M A Aref

Publications and source records attributed to M A Aref.

6 recordsLinked to original sources
PubMed1996

A localised morphoea/idiopathic polymyositis overlap.

A 54-year-old female presented with a three-year history of proximal muscle weakness and arthralgia. EMG, muscle enzymes and biopsy and other tests were consistent with idiopathic polymyositis. At a later stage, she developed plaques of morphoea involving the dorsum of hands and forearms. There was no evidence of systemic sclerosis throughout the course of the disease. In our opinion, such association appeared as an unusual overlap syndrome that provided a new constellation of features in connective tissue disease.

Female↗
PubMed1993

Disease profile of 400 institutionalized mentally retarded patients in Kuwait.

In this preliminary report we summarize the results of a 4-year multidisciplinary systematic, etiological clinicogenetic survey of 400 institutionalized mentally retarded patients in Kuwait. All had an intelligence quotient below 50. A constitutional disorder, as the direct cause of the mental retardation, was found in 203 patients (50.75%)): a chromosomal abnormality in 37 (9.25%), Mendelian disorders in 137 (34.25%), MCA/MR in 22 (5.55%) and CNS malformations in 7 cases (1.75%). In 157 patients (39.35%) a pre-, peri or postnatal cause was ascertained. No etiological diagnosis was detected in 40 patients (10%). A detailed analysis of the "disease profile" is given and compared with the results of previous diagnostic genetic surveys among different institutionalized mentally retarded populations in Western and developing countries.

Abnormalities, Multiple↗
PubMed1980

Pipothiazine palmitate in the long-term treatment of schizophrenia.

Fifty patients suffering from active schizophrenic episodes were treated with electroplexy and thioproperazine for 3 weeks. Pipothiazine palmitate was then given parenterally at a dose of 100 mg at 4-week intervals over a period of 3 years. It seemed to be effective in maintaining remissions in forty-eight patients.

Adult↗