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Biomedical subjects

M A Barnadas

Publications and source records attributed to M A Barnadas.

46 records · Page 3Linked to original sources
PubMed1989

[Woolly hair nevus associated with systemic epidermal nevus].

A 22-year-old female with two woolly hair nevus of the scalp and a systematized epidermal nevus is reported. This association has been rarely described. Scanning electron microscopy of the woolly hair demonstrates oval and triangular hair shaft sections and longitudinal grooves. The structure of the cuticle was not disturbed.

Adult↗
PubMed1988

Clear cell basal cell epithelioma: light and electron microscopic study of an unusual variant.

We report the light and electron microscopic study of 7 examples of an unusual clear cell variant of basal cell epithelioma (BCE). The clear cells show cytoplasmic vacuoles that contain glycogen but do not stain with mucicarmine or fat stains. By electron microscopy the cytoplasmic vacuoles consist of empty spaces not surrounded by membranes. The clear cell pattern may occupy all or part of a given tumor. Typical nodular BCE was found in all 7 cases, but not in every section. Some nodules were composed of mixed solid and clear cell types. Differentiation of this uncommon variant from other clear cell tumors is important.

Aged↗
PubMed1988

Eosinophilic pustulosis: a case report.

A 16-year-old female had a chronic cutaneous eruption clinically characterized by papules, pustules and large exudating plaques of 2 years duration. Multiple biopsies showed infiltration of the follicular epithelium by eosinophils and intraepidermal pustules with neutrophils and eosinophils that were accompanied either by acantholysis or spongiosis. Eosinophilia and hypoproteinemia were detected. A definite infectious etiology or autoimmune mechanism could not be established. Differential diagnosis with other entities that share some clinico-pathological and immunological features are discussed.

Adolescent↗
PubMed1988

[Actinic reticuloid. Immunohistochemical study].

A patient that fulfilled the clinical and histological features of actinic reticuloid has been studied. He presented a positive patch test for fragance mix. Typical cutaneous lesions were reproduced with a solar simulator. The immunochemical studies of the inflammatory infiltrates of these induced lesions gave a higher percentage of T8 in relationship to T4 lymphocytes. Most of the cells were HLA-DR positive. No clonality of these lymphocytes was detected. In the peripheral blood lymphocytes, an increased percentage of T8 lymphocytes was also observed.

Exudates and Transudates↗
PubMedDate not supplied

Cutaneous ulcers with type I cryoglobulinemia treated with plasmapheresis.

Severe necrotic cutaneous ulcers and kidney involvement secondary to type I cryoglobulinemia can be a therapeutic challenge. Plasmapheresis has been reported useful to treat autoimmune diseases such as thrombotic thrombocytopenic purpura, systemic lupus erythematosus, myasthenia gravis and Goodpasture's syndrome. We report the case of a patient who presented necrotic lesions with kidney involvement due to type I cryoglobulinemia (Ig G kappa) that evolved to a multiple myeloma. Treatment with high doses of corticosteroid plus cyclophosphamide did not control the disorder. Therapy with plasmapheresis produced a marked decrease in cryoglobulin levels and a subsequent relevant clinical improvement of cutaneous lesions and renal function. In cryoglobulinemia, plasmapheresis can be used as effective adjunt therapy to minimize cutaneous, renal and/or neurologic involvement.

Aged↗