PubMed Health⌕ Search

Biomedical subjects

M A Elliott

Publications and source records attributed to M A Elliott.

14 recordsLinked to original sources
PubMed1994

Heterogeneity of alpha 1-acid glycoprotein in rheumatoid arthritis.

alpha 1-Acid glycoprotein (AGP) or orosomucoid is a major serum glycoprotein, of unknown physiological function, which is classified as one of the positive acute phase reactants since its plasma concentration becomes elevated two- to five-fold in certain disease states. Additionally, the proportions and identities of the five asparaginyl-linked complex oligosaccharide chains are altered during several physiological and pathological conditions, which may be functionally significant. The key to studying the structural heterogeneity of AGP is to develop a procedure that will isolate AGP without structural degradation. We have developed a method for the purification of AGP, using procedures unlikely to damage the glycoprotein structure, which was utilised to isolate AGP from samples of normal and rheumatoid plasma. The effectiveness of the purification procedure was examined by enzymatically deglycosylating each sample of AGP and separating the released oligosaccharides by chromatography on a pellicular high-performance anion-exchange (HPAE) resin at pH 13. The analytical profile for normal AGP was consistent with that previously reported thus indicating that the purification procedure did not denature the oligosaccharide chains of AGP. Additionally, there was a noticeable difference between the profiles for AGP from normal and rheumatoid plasma.

Arthritis, Rheumatoid↗
PubMed1994

Managing a mid-career crisis.

Recognizing career and life stages can enable individuals to ensure a smooth mid-career transition. Working together, nurses and the organization identify individual needs and potential causes of mid-career crisis as a self-managed career concept is formed.

Career Mobility↗
PubMed1991

Professional responsibility in sports dentistry.

Our professional responsibility related to sports dentistry extends beyond the office. By our active involvement in continuing dental education, we can become more knowledgeable in this relatively new area of sports dentistry. Although it is still in its infancy, sports dentistry is an ever-expanding field. As dentists in practice, whether as general practitioners, specialists, academicians, or researchers, each one of us has a professional responsibility to become involved. Sports dentistry is certain to be a part of our future.

Adolescent↗
PubMed1990

Odontodysplasia in a pediatric patient: literature review and case report.

A case of a three-year-old Caucasian male with odontodysplasia is presented. Although the etiology of this condition is unknown, this anomaly involves both the mesodermal and ectodermal dental components and results in deficient and abnormal formation of dentin and enamel. The orofacial characteristics and dental findings of the condition are presented in this case report.

Child, Preschool↗
PubMedDate not supplied

A comparison of postoperative recovery times between isoflurane and enflurane for pediatric dental outpatient anesthesia.

Isoflurane is a volatile liquid anesthetic agent reported to have recovery times shorter than many anesthetic agents in current use. This study compared postoperative recovery times in pediatric patients receiving dental treatment under isoflurane to those receiving enflurane anesthesia. The study consisted of a retrospective review of anesthesia records for pediatric patients receiving isoflurane anesthesia. These patients were then matched to patients receiving enflurane anesthesia for age, weight, sex, race, and treatment time. A total of nine matched pairs were available for review. The average recovery time (as measured from extubation to discharge) for isoflurane was 53 minutes and for enflurane, 46 minutes. When the matched cases were analyzed by paired t-text, no statistically significant difference in recovery times was demonstrated at the 0.05 level. These findings suggest that there is no significant difference in postoperative recovery times between isofluane and enflurane in pediatric dental outpatients undergoing general anesthesia.

Ambulatory Care↗
PubMedDate not supplied

Stevens-Johnson syndrome: report of case with abnormal root development.

Radiographic follow-up of a Caucasian, Philippino descendent boy revealed abnormal dental development. At the age of four years the apices of second primary molars were still open; at the age of eight years a late, slow, and irregular dental development, unrelated to any systemic disease, was confirmed.

Adult↗
PubMedDate not supplied

Prevalence of selected pediatric conditions in children with Pierre Robin sequence.

Pierre Robin sequence (PRS) is a congenital abnormality characterized by micrognathia and glossoptosis, with or without cleft palate. Patients with PRS may demonstrate various pediatric conditions such as associated syndromes, respiratory distress, feeding difficulties, or middle ear pathology. The purpose of this study was to determine, by means of a retrospective computerized review of patient records, the presence of these pediatric conditions in a sample of 55 confirmed patients with PRS. Five patients (9.1%) exhibited associated syndromes; 20 (36.4%) had respiratory distress requiring no assistance; and 10 (18.2%) exhibited severe respiratory distress requiring tracheotomy. A total of 30 patients (54.5%) had early feeding difficulties requiring mechanical assistance to maintain adequate nutrition, and 50 (90.9%) had multiple episodes of otitis media. Chi-square analysis revealed a statistically significant relationship between the presence of respiratory difficulties and the need for feeding assistance (P = 0.012); and a highly significant relationship between the presence of otitis media and subsequent myringotomy tube placement (P < 0.001). Pediatric dentists who treat children with PRS should be aware of these relationships when obtaining medical history before establishing strategies to implement a treatment plan.

Bottle Feeding↗