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Biomedical subjects

M A Elshina

Publications and source records attributed to M A Elshina.

14 recordsLinked to original sources
PubMed1975

[Comparison of the physiological and biochemical indices of the phagocytosis of ram erythrocytes by macro- and microphages].

Morita and Perkins' method was applied to the study of the stage of ingestion and destruction of an antigen (sheep erythrocytes) in the macrophages of peritoneal exudate of rabbits and rats and in the microphages of rabbit pleural exudate. Ingestion and intracellular destruction of the antigen were accompanied by intensified respiration and glycolysis of phagocytes. Respiration of the three types of phagocytes at two stages of phagocytosis and also the digestive capacity of microphages proved to be sensitive to cyanide and colchicine. The latter failed to influence the ingestion of the antigen by the three types of phagocytes and its digestion by macrophages. The differences in the metabolism routes of macro- and microphages in intracellular destruction of the antigen was postulated. An intensification of the phagocytic activity after the immunization was characteristic of rabbit and rat macrophages.

Animals↗
PubMed1975

[Results of a quantitative study of the interaction of pathogenic enterobacteria with a cell monolayer].

A study was made of the cytopathic effect and dynamics of intracellular reproduction of S. typhimurium and shigellae in the monolayer of HeLa cells, macrophages (monocytes) of the peritoneal exudate of rabbits and rats and microphages (granulocytes) of the pleural exudate of rabbits. The presence of bactericidal mechanism in the host cell to the invaded infectious agent is postulated. An important role of the cell component of defence in insensibility in shigellosis is supposed.

Animals↗
PubMedDate not supplied

[Effect of hindbrain structures on autogenous periodic motor activity in the rat pup].

Experiments were performed in order to investigate whether the capacity of periodic motor excitation in rats during early postnatal life is the intrinsic feature of immature spinal cord or it is caused by supraspinal input. It was shown that after low spinal cord transection, birsts of periodic activity can still be obtained in m. gastrocnemius but their duration and amplitude are significantly reduced. After brain stem transection at intercollicular level, this type of activity remains unchanged or slightly increased. It was concluded that periodic motor excitation is due to the spinal mechanisms but bulbo-spinal facilitative influences are necessary for normal intensity of autogenic activity.

Animals↗
PubMedDate not supplied

[Effect of stimulation of the sensomotor cortex on the activity of the lumbar motor center in rats during ontogenesis].

In rats ageing up to 3 weeks, studies have been made on the reactions of the spinal motor center to long-lasting rhythmic stimulation of sensorimotor cortex. It was found that in 5-day old rats specific periodic pattern of the activity may be recorded similar to the autorhythmic spontaneous activity described in our earlier papers. In older animals periodic pattern of reaction can also be observed, but it may be modulated by stimulation. Beginning from the 12th day, periodic pattern of reaction is transformed into aperiodic one typical for adult animals. From the 3rd week of life, the inhibitory effect of motor cortex stimulation on locomotor activity could be observed.

Age Factors↗
PubMedDate not supplied

[Periodicity of corticospinal motor reactions of rat pups].

It has been demonstrated that at early stages of postnatal development of rats, corticospinal effects interact with spinal automatism. Epicortical stimulation at a frequency 0.5-1/s causes the onset of periodic motor activity during the first week of postnatal life; at later stages the same stimulation evokes periodically changing (with respect to their intensity) motor responses which follow the rhythm of stimulation. It is suggested that autogenic periodic processes in the spinal cord manifest themselves not only in periodic motor excitation, but in periodic changes of excitability as well.

Aging↗