Biomedical subjects

M A Gleĭzer

Publications and source records attributed to M A Gleĭzer.

3 recordsLinked to original sources

PubMed1988

[Autonomic dysfunction in patients with temporal lobe epilepsy].

In 102 patients with temporal epilepsy autonomic (tone, responses, effectiveness) and sympathoadrenal (urine excretion of catecholamines and its changes under effects of epinephrine, insulin and L-DOPA administration) systems were investigated. Some of the indices under study showed reliable correlations with clinical data. Pronounced alterations of autonomic functions were found. The data suggest an important role of catecholamines in the pathogenesis of temporal epilepsy.

Adolescent↗

PubMed1983

[Reactivity of the DOPA--dopamine--noradrenaline--adrenaline system in epileptics].

Epileptic patients were examined for the daily urine elimination of DOPA, dopamine (DA), noradrenaline (NA), and adrenaline (A). The changes in the excretion of these substances after L-DOPA intake and the adrenaline and insulin test were also investigated. In addition to the evidence about the preserved reactivity of the DOPA-DA-NA-A system to L-DOPA intake, data were obtained pointing to its strain and a reduction in the reserve potentialities. The use of the adrenaline test disclosed the absence of, or a negative response on the part of DA and A in half of the patients, which correlated with definite clinical parameters. In one third of the patients, the insulin test was not accompanied by any increase in the excretion of A or its precursors. The findings obtained are indicative of the insufficiency of homeostatic reactions in epileptics and, possibly, of the deficit of the repolarizing mechanisms.

Adolescent↗

PubMed1980

[Petit mal status epilepticus with unusual clinical manifestations].

A unique observation of an epileptic female examined in detail in a neurological clinic is presented. The patient was later hospitalized 3 times for disturbances of consciousness and extrapyramid disorders characterized by acute onset. An encephalographic examination carried out during such a state showed an epileptic status of atypic absence. The development of the Parkinsonian syndrome is regarded as a proof of the role of the caudate nucleus in the genesis of the petit mal epileptic status.

Adult↗