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Biomedical subjects

M A Gurer

Publications and source records attributed to M A Gurer.

4 recordsLinked to original sources

Serum interleukin 18 and tumour necrosis factor-alpha levels are increased in Behcet's disease.

Inflammation in Behcet's disease is thought to be mediated by cytokines derived from T-helper type 1 (Th1) lymphocytes. In this study, we tried to determine serum interleukin (IL)-18 and tumour necrosis factor (TNF)-alpha levels of patients with Behcet's disease. Twenty-seven patients with active Behcet's disease, and 20 healthy control subjects were included in this study. Differences between mean serum IL-18 and TNF-alpha level of patients with Behcet's disease were significantly increased when compared with the control group. A significant correlation was found between serum IL-18 and TNF-alpha levels of Behcet patients (rs = 0.627, P < 0.0001). IL-18 and TNF-alpha levels may be related to disease pathogenesis. Increased levels of IL-18 also support Th1 predominance in Behcet's disease.

Adult↗

Decompression for the management of onychocryptosis.

BACKGROUND: There are many therapeutic alternatives for the management of onychocryptosis. Generally in severe cases, surgical approaches are preferred. OBJECTIVE: The aim of this study was to introduce the new surgical method that treats onychocryptosis without inducing a permanent injury to the matrix. MATERIALS AND METHODS: Twenty-two patients with 30 cases of onychocryptosis were treated by unilateral soft tissue resection combined with partial nail plate avulsion technique without permanent matricectomy. RESULTS: Complete recovery was attained in 25 (83.3%) of cases. No complication was observed. CONCLUSION: The most important advantage of this method was on the nail matrix. No permanent injury is incurred on the matrix.

Adolescent↗

Reticulate acropigmentation of Kitamura: two case reports.

BACKGROUND: Reticulate acropigmentation of Kitamura (RAK) is an autosomal dominantly inherited dermatosis. CASE REPORTS: Two patients are described with the clinical and histopathologic features of reticulate acropigementation of Kitamura. CONCLUSIONS: We speculate that RAK and the Dowling-Degos disease (DDD) are the same diseases.

Adult↗