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Biomedical subjects

M A Gurevich

Publications and source records attributed to M A Gurevich.

At least 19 recordsLinked to original sources
PubMed1991

[Clinico-morphological characteristics of pericardial mesothelioma].

The authors describe clinical and morphological features of a rare tumor, pericardial mesothelioma. Their findings lead them to a conclusion that the epithelioid cell form (tubular and papillary variants) is the most incident histologic form of this tumor. They emphasize that life-time diagnosis of pericardial mesothelioma is of paramount importance because rational chemotherapy permits prolongation of the patient's survival.

Adult↗
PubMed1991

[Clinico-morphological characteristics of dilated cardiomyopathy].

The paper presents the results of a clinicomorphological study of 50 patients with dilated cardiomyopathy. ECG, echocardiography, x-ray revealed atrial fibrillation, parasystole, extrasystole, impairment of intraventricular conduction, symptoms of a focal cicatricial myocardial lesion, high end-systolic and end-diastolic volumes, reduced ejection fraction, marked axial dilatation of the heart. Morphologic evaluation showed diffuse and diffuse microfocal cardiosclerosis, combination of sites of hypertrophic myocardiocytes with dystrophic foci, atrophy, sclerosis. Morphological evidence is available for arrhythmic, cardiomegalic, aneurysmic, infarction-like and pseudovalvular dilated cardiomyopathy.

Adult↗
PubMed1991

[Cardiogenic shock in dilated cardiomyopathy].

The present communication is based on an examination of 33 cases with dilated cardiomyopathy and 48 with severe myocarditis. Nine patients with dilated cardiomyopathy were diagnosed as having developed cardiogenic shock. Clinical examination, echocardiography, right heart and pulmonary artery probing were performed. Cardiogenic shock in dilated cardiomyopathy was demonstrated to be characterized by a progressive decrease in cardiac contractility, no increase in peripheral vascular resistance, and high pulmonary hypertension. Profound cardiomyocyte alterations followed by increased fibrosis of intermuscular and perivascular spaces contribute to the development of cardiogenic shock in dilated cardiomyopathy.

Adult↗
PubMed1991

[Pulmonary hypertension and myocardial contractility in myocarditis].

Hemodynamic studies by direct and indirect methods in patients with myocarditis have revealed that as pulmonary hypertension developed, right-ventricular myocardial contractility and pulmonary arteriolar bed elasticity were decreasing. High pulmonary hypertension and structural shifts in pulmonary artery wall reduced the volumic potentialities of the lesser circulation. The antiorthostatic test was found an important test for the detection of compensatory deposition potentialities of the lesser circulation vessels in myocarditis patients.

Adolescent↗
PubMed1990

[Mechanisms of lesions of myocardial contractility in infectious-allergic myocarditis].

Clinical and morphologic analysis of 63 biopsy specimens and of 23 autopsy specimens has shown the leading role of immune inflammation with the development of delayed and immediate type hypersensitivity in injury to myocardial contractility. It is the immune inflammation that is responsible for disorders in electrolyte metabolism, microcirculation, sympathetic nervous system reactivity.

Autopsy↗
PubMed1989

[Correlation analysis of hemodynamic and morphological parameters in patients with myocarditis].

Central and intrapulmonary hemodynamic parameters were examined in 40 patients with myocarditis. Morphological evidence for endomyocardial biopsy specimens and morphometric findings were also analyzed. Deterioration of myocardial diastolic relaxation was found to closely correlate with the magnitude of cardiosclerotic changes and cardiomyocytic myolysis. A correlation was also established between the morphometric characteristics of the microcirculatory bed and the parameters of myocardial contractility. Functionally deficiently cardiomyocytic hypertrophy was more profound in severe heart failure.

Adolescent↗
PubMed1989

[Bioenergetics of the myocardiocytes in infectious-allergic myocarditis].

The role of myoglobin in myocardial bio-energetics was analyzed in cases of infectious-allergic myocarditis (38 endomyocardial biopsies and 18 autopsies). Myoglobin content is found to be directly related to the severity of the disease and the degree of circulatory compensation or decompensation. In conditions of progressive muscular cell dystrophy, an abrupt drop in myoglobin, detectable around the A discs, can be seen. In hypertrophic myocardiocytes of compensated circulation, myoglobin is detected as distinctly outlined large and small granules.

Adult↗
PubMed1989

[Myocardial insufficiency in infectious-allergic myocarditis].

The authors analyze the results of histologic and electron-microscopic studies of 58 endomyocardial biopsy specimens, obtained from patients with infectious allergic myocarditis aged 20 to 52. Morphologic examinations have been parallelled by studies of arrhythmias in these patients. The major parameters of hemodynamics at rest and dosed exercise have been examined by the radionuclide technique. Cardiac rhythm and conductivity disorders in infectious allergic myocarditis often aggravate the course of the disease, disturb the hemodynamics, and are prognostically unfavourable signs. These disorders result from changes in the myocardial membranes, and one of the mechanisms responsible for the membranous injuries are the dystrophic processes in the nerve fibres, terminals, and receptors of the myocardium.

Adult↗