Biomedical subjects

M A Hayman

Publications and source records attributed to M A Hayman.

3 recordsLinked to original sources

PubMed1980

The classification of affective disorders--a reassessment of the bipolar-unipolar dichotomy. A clinical, laboratory, and family study.

We studied a sample of 26 unipolar and 134 bipolar probands for a selection of familial, demographic, clinical and laboratory variables. We found a high proportion of unipolar illness in the relatives of bipolar probands and bipolar illness in the relatives of unipolar probands, inconsistent with the present dichotomous classification of affective disorders. The two groups were also similar on a number of clinical and demographic variables, and displayed equal amounts of cortical dysfunction as measured by electroencephalographic and neuropsychological techniques. The groups differed significantly on only 2 variables, with unipolars having a greater proportion of females and a later onset age than bipolars. We interpret these findings to be suggestive of homogeneity rather than heterogeneity for the more severe forms of affective disorders and offer several alternatives to the present unipolar/bipolar dichotomy which require further testing.

Adult↗

PubMed1979

Unipolar mania revisited.

In a more sophisticated replication of an earlier study (Abrams and Taylor 1974), we examined 77 manic patients, of whom 29 had never suffered a depressive illness, and had two or more manic attacks. These unipolar manics were similar to the 48 bipolar manics for a wide variety of clinical, phenomenological, historical, laboratory and demographic variables, generally supporting our earlier findings. However, the present sample showed a striking excess of males among the unipolar manics, as well as an increased morbid risk for unipolar depression in first-degree relatives. Although not readily explainable, these differences suggest that it is premature to equate unipolar mania with classical bipolar illness. Further studies of unipolar mania are in progress.

Adult↗

PubMed1977

Capgras' syndrome and cerebral dysfunction.

Two cases of Capgras' syndrome in association with coarse brain disease are presented. The authors suggest that prosopagnosia (face nonrecognition) may be the primary expression of a specific cerebral dysfunction which forms the basis for a delusional elaboration resulting in Capgras' syndrome.

Adult↗