Biomedical subjects

M A Idiazábal-Alecha

Publications and source records attributed to M A Idiazábal-Alecha.

3 recordsLinked to original sources

PubMed2006

[Language processing in attention deficit hyperactivity disorder].

INTRODUCTION: Attention deficit hyperactivity disorder (ADHD) is a heterogeneous condition and often coexists with other disorders that may go undetected, such as communication and language disorders. AIMS: The aim of this study was to evaluate semantic processing of language in children with ADHD by recording the N400 component of cognitive evoked potentials. SUBJECTS AND METHODS: The N400 component was recorded in visual mode while a semantic congruence/ incongruence task was being performed by a sample of 36 children with ADHD and 36 control children. RESULTS: Latency and amplitude of the N400 component were seen to increase and decrease, respectively, in all areas of the brains of the children with ADHD with respect to the children from the control group. CONCLUSIONS: These findings clearly reveal the existence of a deficit in the semantic processing of language in children with ADHD that is associated to their attentional dysfunction.

Attention Deficit Disorder with Hyperactivity↗

PubMed2005

[The value of cognitive evoked potentials in assessing the effectiveness of methylphenidate treatment in children with attention deficit hyperactivity disorder].

AIM: To investigate the changes of the latency and amplitude of P300 in relation to methylphenidate (MPH) medication. SUBJECTS AND METHODS: 36 children with attention deficit hyperactivity disorder (ADHD) and 18 children as control group were tested with an auditory and visual oddball paradigm both before and 1.5 h after a single dose trial of MPH. RESULTS: MPH increased the amplitude and the latency of the visual and auditory P300 component In the ADHD group the latency of the P300 component was longer and the amplitude smaller than in the control group. CONCLUSION: These results suggests that MPH acts to improve processing of cognitive information in children with ADHD where no differences with normal children are present.

Attention Deficit Disorder with Hyperactivity↗

PubMedDate not supplied

[Best practice guidelines for the early detection of Autistic Spectrum Disorders (I)].

INTRODUCTION: The interest in early detection of Autism Spectrum Disorders (ASD) lies in the accumulated evidence of the fact that an early customized intervention for children with an ASD and their families leads to an improvement of the child's prognosis in most cases. OBJECTIVE: To establish criteria and procedures for early identification of children at risk of ASD and to facilitate full diagnostic assessment and prompt referral leading to adequate support. Early detection of ASD is extremely important, since early specific individualized treatment for the child and his or her family leads to long-term improvement in many children' prognosis. DEVELOPMENT: Firstly, a critical appraisal of the situation of early detection of ASD in Spain is made after reviewing the scarce bibliography available on current screening and diagnostic practices in the country. Data generated by questionnaires received from 646 Spanish families is also taken into account. Secondly, the Study Group of the Instituto de Salud Carlos III recommends the screening and early diagnosis process to be followed, describing the necessary steps, the public services involved and the available screening and diagnostic tools. CONCLUSIONS: The Study Group draws the main conclusions regarding the situation of ASD early detection in Spain, and makes a consensus proposal for the detection procedures, including routine developmental surveillance and identification of children at risk for ASD by using sensitive and specific assessment tools.

Child↗